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The two main fluid compartments are the intracellular and extracellular compartments. The intracellular compartment is the space within the organism's cells; it is separated from the extracellular compartment by cell membranes. [1] About two-thirds of the total body water of humans is held in the cells, mostly in the cytosol, and the remainder ...
Extracellular fluid makes up about one-third of body fluid, the remaining two-thirds is intracellular fluid within cells. [3] The main component of the extracellular fluid is the interstitial fluid that surrounds cells.
A lean 70 kg (150 lb) man, for example, has about 42 (42–47) liters of water in his body. The total body of water is divided into fluid compartments , [ 1 ] between the intracellular fluid compartment (also called space, or volume) and the extracellular fluid (ECF) compartment (space, volume) in a two-to-one ratio: 28 (28–32) liters are ...
Jackson's texts states 70% of body fluid is intracellular. [10] Extracellular fluid (1/3 of body water) is fluid contained in areas outside of cells. For a 40-litre body, about 15 litres is extracellular, [9] which amounts to 37.5%. Plasma (1/5 of extracellular fluid). Of this 15 litres of extracellular fluid, plasma volume averages 3 litres ...
In cell biology, molecular biology and related fields, the word extracellular (or sometimes extracellular space) means "outside the cell". This space is usually taken to be outside the plasma membranes, and occupied by fluid (see extracellular matrix). The term is used in contrast to intracellular (inside the cell).
The intracellular calcium level is kept relatively low with respect to the extracellular fluid, by an approximate magnitude of 12,000-fold. This gradient is maintained through various plasma membrane calcium pumps that utilize ATP for energy, as well as a sizable storage within intracellular compartments.
As cell membranes in general are freely permeable to water, the osmolality of the extracellular fluid (ECF) is approximately equal to that of the intracellular fluid (ICF). Therefore, plasma osmolality is a guide to intracellular osmolality.
V ECF a = Extracellular fluid volume after fluid loss; n ECF a = Amount of substance in ECF after fluid loss; V ECF b = Extracellular fluid volume before fluid loss (approximately 20% of body weight, or by using inulin) Osm b = Body osmolarity before loss (almost equal to plasma osmolality of 275-299 milli-osmoles per kilogram [4])