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  2. Acetyl-CoA - Wikipedia

    en.wikipedia.org/wiki/Acetyl-CoA

    In addition, acetyl-CoA is a precursor for the biosynthesis of various acetyl-chemicals, acting as an intermediate to transfer an acetyl group during the biosynthesis of those acetyl-chemicals. Acetyl-CoA is also involved in the regulation of various cellular mechanisms by providing acetyl groups to target amino acid residues for post ...

  3. Acetyl-CoA synthetase - Wikipedia

    en.wikipedia.org/wiki/Acetyl-CoA_synthetase

    ATP + Acetate + CoA → AMP + Pyrophosphate + Acetyl-CoA [1] Once acetyl-CoA is formed it can be used in the TCA cycle in aerobic respiration to produce energy and electron carriers. This is an alternate method to starting the cycle, as the more common way is producing acetyl-CoA from pyruvate through the pyruvate dehydrogenase complex.

  4. Acetoacetyl-CoA synthase - Wikipedia

    en.wikipedia.org/wiki/Acetoacetyl-CoA_synthase

    Acetoacetyl-CoA synthase (EC 2.3.1.194, NphT7) is an enzyme with systematic name acetyl-CoA:malonyl-CoA C-acetyltransferase (decarboxylating). [1] This enzyme catalyses the following chemical reaction

  5. Wood–Ljungdahl pathway - Wikipedia

    en.wikipedia.org/wiki/Wood–Ljungdahl_pathway

    Two specific enzymes participate on the carbon monoxide side of the pathway: CO dehydrogenase and acetyl-CoA synthase. The former catalyzes the reduction of the CO 2 and the latter combines the resulting CO with a methyl group to give acetyl-CoA. [2] [1] [3] Some anaerobic bacteria use the Wood–Ljungdahl pathway in reverse to break down acetate.

  6. Mevalonate pathway - Wikipedia

    en.wikipedia.org/wiki/Mevalonate_pathway

    The mevalonate pathway of eukaryotes, archaea, and eubacteria all begin the same way. The sole carbon feed stock of the pathway is acetyl-CoA. The first step condenses two acetyl-CoA molecules to yield acetoacetyl-CoA. This is followed by a second condensation to form HMG-CoA (3-hydroxy-3- methyl-glutaryl-CoA). Reduction of HMG-CoA yields (R ...

  7. Acetate CoA-transferase - Wikipedia

    en.wikipedia.org/wiki/Acetate_CoA-transferase

    In enzymology, an acetate CoA-transferase (EC 2.8.3.8) is an enzyme that catalyzes the chemical reaction acyl-CoA + acetate ⇌ {\displaystyle \rightleftharpoons } a fatty acid anion + acetyl-CoA Thus, the two substrates of this enzyme are acyl-CoA and acetate , whereas its two products are long-chain carboxylate anion and acetyl-CoA .

  8. Acetyl-CoA C-acetyltransferase - Wikipedia

    en.wikipedia.org/wiki/Acetyl-CoA_C-acetyltransferase

    In enzymology, an acetyl-CoA C-acetyltransferase (EC 2.3.1.9) is an enzyme that catalyzes the chemical reaction. 2 acetyl-CoA CoA + acetoacetyl-CoA. Hence, this enzyme has one substrate, acetyl-CoA, and two products, CoA and acetoacetyl-CoA. Acetyl-CoA C-acetyltransferase belongs to the thiolase family of enzymes.

  9. Acetyl group - Wikipedia

    en.wikipedia.org/wiki/Acetyl_group

    In biological organisms, acetyl groups are commonly transferred from acetyl-CoA to other organic molecules. Acetyl-CoA is an intermediate in the biological synthesis and in the breakdown of many organic molecules. Acetyl-CoA is also created during the second stage of cellular respiration (pyruvate decarboxylation) by the action of pyruvate ...

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