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Mucocutaneous leishmaniasis is an especially disturbing form of cutaneous leishmaniasis, because it produces destructive and disfiguring lesions of the face. It is most often caused by Leishmania braziliensis, but cases caused by L. aethiopica have also been described. [10] Mucocutaneous leishmaniasis is very difficult to treat.
Leishmaniasis is a wide array of clinical manifestations caused by protozoal parasites of the Trypanosomatida genus Leishmania. [7] It is generally spread through the bite of phlebotomine sandflies, Phlebotomus and Lutzomyia, and occurs most frequently in the tropics and sub-tropics of Africa, Asia, the Americas, and southern Europe.
Leishmania braziliensis, like other species of Leishmania, rely on asexual reproduction in the intermediate mammalian host to greatly increase population density. Such reproduction is often witnessed in mononuclear phagocytes (dendritic cells, monocytes, neutrophils) of the mammalian host, with the macrophages being the target white blood cell of the parasite. [5]
It is estimated that visceral leishmaniasis (VL) affects more than 100 million people worldwide, [37] with 1.5 to 2 million new cases and more than 70,000 deaths each year. [38] As of the 2022 report, there were 50,000 to 90,000 infections worldwide in 2020, and the World Health Organization estimates that only between 25 and 45% of the cases ...
ingestion of water containing deer or beaver feces Isosporiasis: Isospora belli: epithelial cells of small intestines: stool worldwide – less common than Toxoplasma or Cryptosporidium: fecal oral route – ingestion of sporulated oocyst Leishmaniasis: Leishmania spp. cutaneous, mucocutaneous, or visceral
Brahmachari's cure for visceral leishmaniasis was the urea salt of para-amino-phenyl stibnic acid which he called Urea Stibamine. [117] During the nineteenth century, kala-azar was discovered near moving bodies of water in southeast Asia. [118] Dr. Jean Dow and Dr. William McClure, are credited with finding the cure for the disease in China.
Scabies (also sometimes known as the seven-year itch) is a contagious human skin infestation by the tiny (0.2–0.45 mm) mite Sarcoptes scabiei, variety hominis. The word is from Latin: scabere, lit. 'to scratch'. The most common symptoms are severe itchiness and a pimple -like rash. Occasionally, tiny burrows may appear on the skin. In a first-ever infection, the infected person usually ...
After treatment at TPS, effluent is pumped through a 36-inch diameter pipe along an eight-and-a-half mile route to the Southeast Farm. With the oversight of licensed wastewater treatment operators, a computer system controls the center-pivot sprinkler systems and the distribution of water through them.
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