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  2. Cachexia - Wikipedia

    en.wikipedia.org/wiki/Cachexia

    Cachexia (/ k ə ˈ k ɛ k s i ə / [1]) is a syndrome that happens when people have certain illnesses, causing muscle loss that cannot be fully reversed with improved nutrition. [2] It is most common in diseases like cancer, congestive heart failure, chronic obstructive pulmonary disease, chronic kidney disease, and AIDS.

  3. Society on Sarcopenia, Cachexia and Wasting Disorders

    en.wikipedia.org/wiki/Society_on_Sarcopenia...

    Cachexia can occur in most major diseases including infections, cancer, heart disease, chronic kidney disease, chronic obstructive pulmonary disease, and stroke. [51] Skeletal muscle provides a fundamental basis for human function, enabling locomotion and respiration. Muscle wasting is related to poor quality of life and increased morbidity ...

  4. Enobosarm Phase 2 Trial for Muscle Wasting and Physical ... - AOL

    www.aol.com/news/2013-03-14-enobosarm-phase-2...

    Enobosarm Phase 2 Trial for Muscle Wasting and Physical Function in Patients with Cancer Published in The Lancet Oncology Trial demonstrated significant increases in lean body mass (muscle) and ...

  5. Muscle atrophy - Wikipedia

    en.wikipedia.org/wiki/Muscle_atrophy

    Malnutrition first causes fat loss but may progress to muscle atrophy in prolonged starvation and can be reversed with nutritional therapy. In contrast, cachexia is a wasting syndrome caused by an underlying disease such as cancer that causes dramatic muscle atrophy and cannot be completely reversed with nutritional therapy.

  6. I'm A Breast Cancer Doctor. Here's What I Didn't Know - AOL

    www.aol.com/im-breast-cancer-doctor-heres...

    Having counseled thousands of patients through their breast cancer diagnosis, I was fully aware of how nondiscriminatory this disease could be. ... is also crucial to preventing muscle wasting and ...

  7. Tumor necrosis factor - Wikipedia

    en.wikipedia.org/wiki/Tumor_necrosis_factor

    Conditions that cause inflammation, such as cancer, can elevate TNF levels, which contributes to muscle wasting. TNF contributes to muscle wasting by activating the NF-κB pathway, which activates the ubiquitin–proteasome pathway to degrade protein, and by inhibiting the activation of satellite cells, which are responsible for protein ...