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Neonatal jaundice is a yellowish discoloration of the white part of the eyes and skin in a newborn baby due to high bilirubin levels. [1] Other symptoms may include excess sleepiness or poor feeding. [1] Complications may include seizures, cerebral palsy, or kernicterus. [1] In most of cases there is no specific underlying physiologic disorder. [2]
772.9 Unspecified hemorrhage of newborn; 773 Hemolytic disease of fetus or newborn, due to isoimmunization. 773.0 Hemolytic disease, RH isoimmunization; 773.1 Hemolytic disease, ABO isoimmunization; 774 Other perinatal jaundice. 774.2 Jaundice, newborn, prematurity; 774.3 Jaundice, newborn, unspec. 774.3 Lucey-Driscoll syndrome. 774.39 Jaundice ...
If neonatal cholestasis is suspected or an infant is presenting with jaundice after two weeks of life, total and conjugated bilirubin must be measured. [10] Neonatal cholestasis is present if conjugated bilirubin value is >20% of total serum bilirubin or if serum conjugated bilirubin concentration is greater than 1.0 mg/dL. [2]
Jaundice, also known as icterus, is a yellowish or greenish pigmentation of the skin and sclera due to high bilirubin levels. [3] [6] Jaundice in adults is typically a sign indicating the presence of underlying diseases involving abnormal heme metabolism, liver dysfunction, or biliary-tract obstruction. [7]
Neonatal jaundice; Neurofibromatosis; Neuronal ceroid lipofuscinosis; Noonan syndrome; Nystagmus; O ... List of ICD-9 codes 740–759: congenital anomalies; Rare disease
Gilbert syndrome has been reported to contribute to an accelerated onset of neonatal jaundice. The syndrome cannot cause severe indirect hyperbilirubinemia in neonates by itself, but it may have a summative effect on rising bilirubin when combined with other factors, [ 10 ] for example in the presence of increased red blood cell destruction due ...
[10] Bilirubin should be tested from cord blood. [6] Ferritin — because most infants affected by HDN have iron overload, a ferritin must be run before giving the infant any additional iron. [12] Newborn Screening Tests — Transfusion with donor blood during pregnancy or shortly after birth can affect the results of the Newborn Screening Tests.
Lucey–Driscoll syndrome is an autosomal recessive metabolic disorder affecting enzymes involved in bilirubin metabolism. [1] It is one of several disorders classified as a transient familial neonatal unconjugated hyperbilirubinemia. [citation needed]