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The cost of the egg-freezing procedure (without embryo transfer) in the United States, the United Kingdom, and other European countries varies between $5,000 and $12,000. Specifically, in the UK, egg freezing costs range from approximately £3,300 to £3,900 for the procedure, with annual storage fees between £350 and £400. [ 18 ]
In a survey of the North American embryo transfer industry, embryo transfer success rates from direct transfer of embryos were as good as to those achieved with glycerol. [58] Moreover, in 2011, more than 95% of frozen-thawed embryos were transferred by Direct Transfer. [59]
In current state of the art, early embryos having undergone cryopreservation implant at the same rate as equivalent fresh counterparts. [2] The outcome from using cryopreserved embryos has uniformly been positive with no increase in birth defects or development abnormalities, [3] [8] also between fresh versus frozen eggs used for intracytoplasmic sperm injection (ICSI). [9]
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The timeline of reciprocal IVF depends on if a couple chooses to undergo a fresh or a frozen transfer: A fresh embryo transfer IVF cycle lasts around 17–20 days and 10 days after the embryo is transferred to wait for the results of a pregnancy test. [14] A frozen embryo transfer first involves one of the cycles dedicated to the genetic mother.
In 2004 Jacques Donnez in Belgium reported the first successful birth from frozen tissue using a protocol developed in Roger Gosden’s laboratory, where Oktay had studied. In 1997 samples of ovarian cortex were taken from a woman with Hodgkin's lymphoma and cryopreserved by slow freezing (Planer, UK) for banking in liquid nitrogen.
The Alabama Supreme Court has ruled that frozen embryos can be considered children under state law, a decision critics said could have sweeping implications for fertility treatment in the state.
Cryopreservation for embryos is used for embryo storage, e.g., when IVF has resulted in more embryos than is currently needed. One pregnancy and resulting healthy birth has been reported from an embryo stored for 27 years, after the successful pregnancy of an embryo from the same batch three years earlier. [ 39 ]