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This page was last edited on 9 February 2024, at 00:17 (UTC).; Text is available under the Creative Commons Attribution-ShareAlike 4.0 License; additional terms may apply.
A phosphodiesterase-4 inhibitor, commonly referred to as a PDE4 inhibitor, is a drug used to block the degradative action of phosphodiesterase 4 (PDE4) on cyclic adenosine monophosphate (cAMP). It is a member of the larger family of PDE inhibitors .
Pages in category "PDE4 inhibitors" The following 23 pages are in this category, out of 23 total. This list may not reflect recent changes. ...
The different forms or subtypes of phosphodiesterase were initially isolated from rat brains in the early 1970s [1] [2] and were soon afterward shown to be selectively inhibited in the brain and in other tissues by a variety of drugs. [3] [4] The potential for selective phosphodiesterase inhibitors as therapeutic agents was predicted as early ...
Pages in category "Phosphodiesterase inhibitors" The following 40 pages are in this category, out of 40 total. This list may not reflect recent changes. *
Merck & Co's Januvia, used to help lower blood glucose levels in adults with type-2 diabetes, was prescribed to 869,000 patients with Medicare coverage in the year ending June 2023 at a gross cost ...