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A familial tendency to develop autoimmune diseases suggests a genetic component. Some conditions, like lupus and multiple sclerosis, often occur in several members of the same family, indicating a potential hereditary link. Additionally, certain genes have been identified that increase the risk of developing specific autoimmune diseases.
Most autoimmune diseases are sex-related; as a whole, women are much more likely to develop autoimmune disease than men. Being female is the single greatest risk factor for developing autoimmune disease than any other genetic or environmental risk factor yet discovered.
Histone methylation is also implicated in autoimmune disorders. This can be by inhibition of histone methylation such as in systemic sclerosis or by elevated histone methylation at certain gene loci in Type I diabetes. [4] Histone modification can give rise to rheumatic, endocrinological, and gastrointestinal autoimmune disorders.
8 Autoimmune Diseases That Cause Hair Loss. This article was reviewed by Knox Beasley, MD.. You might associate autoimmune conditions with symptoms like skin disease, chronic pain, and fatigue.
Scientists have never been able to explain why women are at such greater risk of autoimmune disease, but new research published in Cell on February 1 could hold the answer. And the key lies in the ...
What experts say about the connection between the immune system and autoimmune disorders like MS, lupus, arthritis, and others.