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Please review the contents of the article and add the appropriate references if you can. Unsourced or poorly sourced material may be challenged and removed . Find sources: "List of long term side effects of antipsychotics" – news · newspapers · books · scholar · JSTOR ( March 2017 )
Antipsychotic abuse refers to the non-medical or inappropriate use of antipsychotic medications for purposes other than their intended therapeutic use. Antipsychotics, also known as neuroleptics, are a class of medications primarily used in treating psychiatric disorders such as schizophrenia , bipolar disorder , and certain types of depression .
In case reports, quetiapine has been abused in doses taken by mouth (which is how the drug is available from the manufacturer), but also crushed and insufflated or mixed with water for injection into a vein. [294] Olanzapine, another sedating second-generation antipsychotic, has also been misused for similar reasons. [294]
Peak levels of quetiapine occur 1.5 hours after a dose. [86] The plasma protein binding of quetiapine is 83%. [86] The major active metabolite of quetiapine is norquetiapine (N-desalkylquetiapine). [67] Quetiapine has an elimination half-life of 6 or 7 hours. [86] [7] [8] Its metabolite, norquetiapine, has a half-life of 9 to 12 hours.
Psychomotor agitation is typically found in various mental disorders, especially in psychotic and mood disorders. It can be a result of drug intoxication or withdrawal. It can also be caused by severe hyponatremia. People with existing psychiatric disorders and men under the age of 40 are at a higher risk of developing psychomotor agitation. [2]
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The atypical antipsychotics (AAP), also known as second generation antipsychotics (SGAs) and serotonin–dopamine antagonists (SDAs), [1] [2] are a group of antipsychotic drugs (antipsychotic drugs in general are also known as tranquilizers and neuroleptics, although the latter is usually reserved for the typical antipsychotics) largely introduced after the 1970s and used to treat psychiatric ...
“Beginning in about December 2018 and persisting through February 2020, Mr. Stern’s three young children were subjected to heinous child abuse at the hands of their own mother, Mr. Stern’s ...