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Notalgia paresthetica is a common localized itch, affecting mainly the area between the shoulder blades (especially the T2–T6 dermatomes) but occasionally with a more widespread distribution, involving the shoulders, back, and upper chest.
The body's need for thyroid hormone can also change over time, such as in the first months after radioactive iodine treatment (RAI). Thyroid autoimmune diseases can also be volatile [citation needed], as hyperthyroidism can interchange with hypothyroidism and euthyroidism. [2]
The back, legs, arms, scalp, and genitalia are areas of the body that are commonly affected by senile pruritus. [3] According to a study, most of the people who experience pruritus daily have increased itching sensations and other associated symptoms during the night. Most studies reveal that senile pruritus is more common in men than women. [3]
Primary treatment is prompted by the administration of adequate doses of either the thyroid hormone L-thyroxine given intravenously or by giving liothyronine via a nasogastric tube. It is essential to identify and treat the condition precipitating the coma. [9] Myxedema coma is rare but often fatal.
The drawback to this treatment is the thyroid gland is completely destroyed and patients often develop hypothyroidism. Some do so only a few months after treatment while others may not be affected for 20–30 years. Hypothyroidism patients must begin a lifelong regimen of thyroid replacement hormones.
Itch in contrast creates a scratch reflex, which draws one to the affected skin site. Itch generates stimulus of a foreign object underneath or upon the skin and also the urge to remove it. For example, responding to a local itch sensation is an effective way to remove insects from one's skin.
Over the course of a year, with treatments every three to six months, the average cost typically ranges from $1,050 to $1,400 for women, and $1,400 to $2,100 for men—bringing the cost per ...
The exact mechanism of the condition is unknown. Some studies have suggested the itching occurs in response to increased fibrinolytic activity in the skin, [5] [6] inappropriate activation of the sympathetic nervous system, [7] increased activity of acetylcholinesterase, [8] [9] or an increase in mast cell degranulation that releases histamine and other chemicals into the body.