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Certain lithium compounds, also known as lithium salts, are used as psychiatric medication, [5] primarily for bipolar disorder and for major depressive disorder. [5] Lithium is taken orally (by mouth). [5] Common side effects include increased urination, shakiness of the hands, and increased thirst. [5]
Excessive levels of lithium can be harmful to the kidneys, and increase the risk of side effects in general. As a result, kidney function and blood levels of lithium are monitored in patients being treated with lithium. [2] Therapeutic plasma levels of lithium range from 0.5 to 1.5 mEq/L, with levels of 0.8 or higher being desirable in acute ...
Lithium Lithium is the "classic" mood stabilizer, the first to be approved by the US FDA, and still popular in treatment. Therapeutic drug monitoring is required to ensure lithium levels remain in the therapeutic range: 0.6 to 0.8 or 0.8–1.2 mEq/L (or millimolar).
The global estimated lifetime prevalence of bipolar disorder among adults range from 1 to 3 percent. [63] The annual incidence is estimated to vary from 0.3 to 1.2 percent worldwide. [23] According to the World Mental Health Survey Initiative, the lifetime prevalence of BP-II was found to be 0.4%, with a 12-month prevalence of 0.3%. [64]
Studies using DSM criteria show that up to 1% of youth may have bipolar disorder. [129] The DSM-5 has established a diagnosis—disruptive mood dysregulation disorder—that covers children with long-term, persistent irritability that had at times been misdiagnosed as having bipolar disorder, [133] distinct from irritability in bipolar disorder ...
Psychiatric disorders, including depression, psychosis, and bipolar disorder, are common and gaining more acceptance in the United States. The most commonly used classes of medications for these disorders are antidepressants, antipsychotics, and lithium. Unfortunately, these medications are associated with significant neurotoxicities.
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