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Secondary amenorrhea's most common and most easily diagnosable causes are pregnancy, thyroid disease, and hyperprolactinemia. [50] A pregnancy test is a common first step for diagnosis. [50] Similar to primary amenorrhea, evaluation of secondary amenorrhea also begins with a pregnancy test, prolactin, FSH, LH, and TSH levels. [13]
In the case of RED-S, the majority of secondary amenorrhea cases are attributed to functional hypothalamic amenorrhea (FHA), an adaptive mechanism to preserve energy for survival and vital processes rather than reproduction when energy balance is low. [17] [18] Primary amenorrhea is characterized by delayed menarche (the onset of menses during ...
A full physical exam, external gynecological and bimanual exam can be performed to assess for organic causes of amenorrhea. [9] Symptoms of hypoestrogenism, whose severity will positively correlate with the duration of hypoestrogenism, will be present in FHA patients; these can include lack of cervical mucus, pale areola and nipples, thinned ...
The progestogen challenge test, or progesterone withdrawal test, is a test used in the field of obstetrics and gynecology to evaluate a patient who is experiencing amenorrhea. Due to readily available assays to measure serum estradiol levels, this test is now rarely used. [1]
Patients experiencing amenorrhea due to hypothyroidism may be started with thyroid replacement therapy. Dopamine agonists such as bromocriptine are used in patients with pituitary adenomas . Amenorrhea associated with gonadal dysgenesis or a hypoestrogenic state may be treated with oral contraceptives, patches, or vaginal rings.
Signs and Symptoms Individuals with XX gonadal dysgenesis appear phenotypical female with normal internal and external genitalia, bilateral streak gonads, and normal stature. Diagnosis commonly occurs in adolescence due to delayed puberty or amenorrhea.
Oligoamenorrhea, also known as irregular infrequent periods or irregular infrequent menstrual bleeding, is a collective term to refer to both oligomenorrhea (infrequent periods) and amenorrhea (absence of periods). [1] It is a menstrual disorder in which menstrual bleeding occurs on an infrequent and irregular basis.
In women, low levels of estrogen may cause symptoms such as hot flashes, sleeping disturbances, decreased bone health, [3] and changes in the genitourinary system. Hypoestrogenism is most commonly found in women who are postmenopausal, have primary ovarian insufficiency (POI), or are presenting with amenorrhea (absence of menstrual periods).
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