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Cetuximab, sold under the brand name Erbitux, is an epidermal growth factor receptor (EGFR) inhibitor medication used for the treatment of metastatic colorectal cancer and head and neck cancer. [2] Cetuximab is a chimeric (mouse/human) monoclonal antibody given by intravenous infusion .
This list of over 500 monoclonal antibodies includes approved and investigational drugs as well as drugs that have been withdrawn from market; consequently, the column Use does not necessarily indicate clinical usage. See the list of FDA-approved therapeutic monoclonal antibodies in the monoclonal antibody therapy page.
Cobimetinib or XL518, approved by US FDA in Nov 2015 for use in combination with vemurafenib (Zelboraf(R)), for treatment of advanced melanoma with a BRAF V600E or V600K mutation. Selumetinib , had a phase 2 clinical trial for non-small cell lung cancer (NSCLC) which demonstrated an improvement in PFS, [ 5 ] and is now in phase III development ...
By Christy Santhosh and Unnamalai L (Reuters) -The U.S. Food and Drug Administration has approved Bristol Myers Squibb's combination therapy for treating colorectal cancer in patients with a ...
The Scottish Medicines Consortium accepted a treatment of colorectal cancer in patients with a gene mutation called ‘BRAF V600’. Medicines for colorectal, skin and ovarian cancers approved for ...
In June 2006, it was approved with 5-fluorouracil-based therapy for second-line metastatic colorectal cancer. [34] It was approved by the European Medicines Agency (EMA) in January 2005, for use in colorectal cancer. [35] [29] Bevacizumab has also been examined as an add on to other chemotherapy drugs in people with non-metastatic colon cancer.
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