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Other causes include vasculitis and in situ thrombosis related to hypercoagulable states. [53] Additional mechanisms of peripheral artery disease include arterial spasm and fibromuscular dysplasia. [19] The cause and pathophysiology of arterial spasm are not fully understood, but it is hypothesised that they can occur secondary to trauma. [54]
The most common cause of CVI is superficial venous reflux, which is a treatable condition. [2] As functional venous valves are required to provide for efficient blood return from the lower extremities, this condition typically affects the legs.
Lack of exercise is another common cause of water retention in the legs. Exercise helps the leg veins work against gravity to return blood to the heart . If blood travels too slowly and starts to pool in the leg veins , the pressure can force too much fluid out of the leg capillaries into the tissue spaces.
The lower legs and the forearms are the most frequent sites affected by compartment syndrome. Other areas of the body such as thigh, buttock, hand, abdomen, and foot can also be affected. [19] [14] The most common cause of acute compartment syndrome is fracture of a bone, most commonly the tibia. [29]
People who sit for long periods of time can benefit from compression leggings as well since they increase blood flow in the legs. Prolonged sitting causes poor circulation, so wearing compression ...
Causes [2] of venous stasis include: Obesity; Pregnancy; Previous damage to leg; Blood clot; Smoking; Swelling and inflammation of a vein close to the skin; Congestive heart failure. [3] Long periods of immobility that can be encountered from driving, [4] flying, bed rest/hospitalization, or having an orthopedic cast.
The prognosis for patients with peripheral vascular disease due to atherosclerosis is poor; patients with intermittent claudication due to atherosclerosis are at increased risk of death from cardiovascular disease (e.g. heart attack), because the same disease that affects the legs is often present in the arteries of the heart. [8]
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