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Cytology can be used to diagnose a condition and spare a patient from surgery to obtain a larger specimen. An example is thyroid FNAC; many benign conditions can be diagnosed with a superficial biopsy and the patient can go back to normal activities right away.
Histopathology (compound of three Greek words: ἱστός histos 'tissue', πάθος pathos 'suffering', and -λογία-logia 'study of') is the microscopic examination of tissue in order to study the manifestations of disease.
Histopathology refers to the microscopic examination of various forms of human tissue. Specifically, in clinical medicine, histopathology refers to the examination of a biopsy or surgical specimen by a pathologist, after the specimen has been processed and histological sections have been placed onto glass slides. [ 17 ]
Histopathology – the microscopic examination of stained tissue sections using histological techniques. The standard stains are haematoxylin and eosin , but many others exist. The use of haematoxylin and eosin-stained slides to provide specific diagnoses based on morphology is considered to be the core skill of anatomic pathology.
Koilocytosis or koilocytic atypia or koilocytotic atypia are terms used in histology and cytology to describe the presence of koilocytes in a specimen. [1] Koilocytes may have the following cellular changes: Nuclear enlargement (two to three times normal size). Irregularity of the nuclear membrane contour, creating a wrinkled or raisinoid ...
With the use of direct immunofluorescence examination, the specificity of cytology for diagnosing pemphigus can be increased from 43% to 100%. Erythema multiforme, Toxic epidermal necrolysis Apoptotic and necrotic cells, absence of acantholytic cells A Tzanck smear may be a rapid test to distinguish toxic epidermal necrolysis from SSSS III.
Pathologists may review samples such as pleural, peritoneal, synovial, or pericardial fluids to characterize them as "normal", tumoral, inflammatory, or even infectious. Microscopic examination can also determine the causal infectious agent – often a bacterium, mould, yeast, parasite, or (rarely) virus.
1 Normal histology. 2 Clear cell cancers. ... In histology, a clear cell is a cell that shows a clear cytoplasm when stained with hematoxylin and eosin (H&E). [1]