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Attention deficit hyperactivity disorder management options are evidence-based practices with established treatment efficacy for ADHD.Approaches that have been evaluated in the management of ADHD symptoms include FDA-approved pharmacologic treatment and other pharmaceutical agents, psychological or behavioral approaches, combined pharmacological and behavioral approaches, cognitive training ...
Drugs that selectively block the reuptake of serotonin and norepinephrine effectively treat depression and are better tolerated than TCAs. TCAs have comprehensive effects on various neurotransmitters receptors, which leads to lack of tolerability and increased risk of toxicity. [2]
Atomoxetine is sometimes used in the treatment of cognitive impairment and frontal lobe symptoms due to conditions like traumatic brain injury (TBI). [48] [49] It is used to treat ADHD-like symptoms such as sustained attentional problems, disinhibition, [50] lack of arousal, fatigue, and depression, including symptoms from cognitive disengagement syndrome. [48]
[1] [2] [3] It is the α-methylated derivative of tryptophan, while αMS is the α-methylated analogue of serotonin. [1] [3] αMTP has been suggested for potential therapeutic use in the treatment of conditions thought by some authors to be related to serotonin deficiency, such as depression. [1]
Tryptophan is sold over the counter in the United States (after being banned to varying extents between 1989 and 2005) and the United Kingdom as a dietary supplement for use as an antidepressant, anxiolytic, and sleep aid. It is also marketed as a prescription drug in some European countries for the treatment of major depression.
The effects of MAEs appear to be mediated by intracellular TAAR1 agonism coupled with uptake by monoamine transporters into monoaminergic neurons. [3] [4] In contrast to amphetamines, IPAP has no classical monoamine releasing agent actions. [1] [3] It is a weak MAO-A inhibitor similarly to BPAP. [1] [2] [5]
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