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Docetaxel is in the taxane family of medications. [9] It works by disrupting the normal function of microtubules and thereby stopping cell division. [6] Docetaxel was patented in 1986 and approved for medical use in 1995. [10] It is on the World Health Organization's List of Essential Medicines. [11] Docetaxel is available as a generic ...
In June 2014, a phase III trial of the drug reported it failed to improve overall survival in liver cancer. [17] In February 2016, it was reported that a phase II trial of adding ramucirumab to docetaxel improved progression-free survival (PFS) compared with docetaxel alone in locally advanced or metastatic urothelial carcinoma. [18]
2004 – bevacizumab, the first approved drug to inhibit blood vessel formation by tumours, is licensed [4] 2005 – US FDA approves taxol for chemotherapy of breast, pancreatic, and non-small cell lung cancers [43] 2006 – US FDA approves herceptin [10] 2007 – US FDA approves sorafenib [10]
Pertuzumab is administered as an intravenous infusion in combination with trastuzumab and docetaxel as a first line treatment for HER2-positive metastatic breast cancer. [4] [3] It is also used in the same combination as a neoadjuvant (given to reduce the size of a tumor, prior to surgery or radiation) for HER2-positive early breast cancer; as of 2016 this use had not been shown to increase ...
On Tuesday, the FDA approved NovoCure’s (NASDAQ:NVCR) Optune Lua for concurrent use with PD-1/PD-L1 inhibitors or docetaxel for adult patients with metastatic non-small cell lung cancer (mNSCLC ...
A study of more than 160,000 women in New Mexico published in Preventative Medicine found that between January 2015 and August 2019, only half who tested positive for cancer-causing HPV cells ...
One study found that disrupting the interaction between two proteins may be the key to blocking neurodegeneration in Parkinson’s disease. ... (FDA)-approved cancer drug already targets Lag3.
March 11, 2011, the US Food and Drug Administration (FDA) approved cancer drug docetaxel, a generic version by Hospira. Taxotere sales were approximately $1.2 billion in 2010. — Preceding unsigned comment added by Ocdncntx ( talk • contribs ) 21:42, 11 March 2011 (UTC) [ reply ]