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Most of the medications impacted by the shortage were generic, low-cost drugs with sterile injectable medications such as chemotherapy agents being the most impacted. [3] Tornado damage to a pharmaceutical manufacturing plant responsible for a large amount of national injectable drug production exacerbated shortages. [1]
Cancer cells can also cause defects in the cellular pathways of apoptosis (programmed cell death). As most chemotherapy drugs kill cancer cells in this manner, defective apoptosis allows survival of these cells, making them resistant. Many chemotherapy drugs also cause DNA damage, which can be repaired by enzymes in the cell that carry out DNA ...
Intrathecal administration is a route of administration for drugs via an injection into the spinal canal, or into the subarachnoid space so that it reaches the cerebrospinal fluid (CSF). It is useful in several applications, such as for spinal anesthesia , chemotherapy , or pain management .
Di Bella Therapy – a cocktail of vitamins, drugs and hormones devised by Luigi di Bella (1912–2003) and promoted as a cancer treatment. According to the American Cancer Society: "Available scientific evidence does not support claims that Di Bella therapy is effective in treating cancer. It can cause serious and harmful side effects. ...
The World Health Organization breaks down the three types of carcinogens that can cause cancer in humans. The first type of carcinogen is the physical type which can be ultraviolet and ionizing radiation. The second type of carcinogens is defined as asbestos, tobacco smoke, alcohol, aflatoxin, and arsenic.
Non-small cell lung cancer, oesophageal cancer, uterine cervical cancer, head and neck cancer and urothelial cancer: Nephrotoxicity, myelosuppression and nausea and vomiting (30-90%). Oxaliplatin: IV: Reacts with DNA, inducing apoptosis, non-cell cycle specific. Colorectal cancer, oesophageal cancer and gastric cancer
Prepare the Injection. This will probably be the most time-consuming step, but it gets easier with practice and should take just a few minutes. Take the sterile cap off the GLP-1 medication and ...
A drawback of treatment is that many genotoxic drugs are effective on cancerous cells and normal cells alike. Selectivity of a particular drug's action is based on the sensitivity of the cells themselves. So, while rapidly dividing cancer cells are particularly sensitive to many drug treatments, often normal functioning cells are affected. [27]