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Low-dose spironolactone is generally very well tolerated. [63] Even higher doses of spironolactone, such as 100 mg/day, are well tolerated in most individuals. [63] Dose-dependent side effects of spironolactone include menstrual irregularities, breast tenderness, and enlargement, orthostatic hypotension, and hyperkalemia. [63]
Spironolactone has been found to be effective in the treatment of hirsutism in women at a dosage of as low as 50 mg/day. [60] At dosages of 100 mg/day and 200 mg/day, observed reductions in hair shaft diameter were 19% ± 8% and 30% ± 3%, respectively ( p = 0.07).
The trial was stopped early because the beneficial effect of spironolactone on all-cause death exceeded the prespecified discontinuation requirements. Spironolactone reduced the risk of death by 30% compared to placebo. Additionally, there was a 35% reduction in the risk of hospitalization for worsening heart failure in the spironolactone group.
Stomach pain is a common symptom of functional dyspepsia. Symptoms: Early satiety, heartburn, nausea, postprandial fullness, vomiting, and/or epigastric pain. [1] Complications: Symptoms of anxiety, depression, and somatization. [2] Types: Postprandial distress syndrome and epigastric pain syndrome. [1] Diagnostic method: Rome IV criteria. [1 ...
Gas-X or simethicone-containing products dissolve excessive gas in the stomach and intestines, helping with the pressure and pain. Tums or Pepcid give instant relief by neutralizing increased acid ...
Experts Explain Exactly Why Pasta In Europe Doesn't Make Your Stomach Hurt. Mackenzie Filson. December 27, 2024 at 8:00 AM ... Japanese fried chicken, and crusty French baguettes without my usual ...