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Aspirin-exacerbated respiratory disease (AERD), also called NSAID-exacerbated respiratory disease (N-ERD) or historically aspirin-induced asthma and Samter's Triad, is a long-term disease defined by three simultaneous symptoms: asthma, chronic rhinosinusitis with nasal polyps, and intolerance of aspirin and other nonsteroidal anti-inflammatory drugs (NSAIDs).
Pain relief starts soon after taking the first dose, and a full analgesic effect should normally be obtained within a week, whereas an anti-inflammatory effect may not be achieved (or may not be clinically assessable) for up to three weeks. If appropriate responses are not obtained within these times, another NSAID should be tried. [3]
[177] [178] People with hemophilia or other bleeding tendencies should not take aspirin or other salicylates. [177] [181] Aspirin is known to cause hemolytic anemia in people who have the genetic disease glucose-6-phosphate dehydrogenase deficiency, particularly in large doses and depending on the severity of the disease. [182]
That was followed by a 2022 recommendation from the U.S. Preventive Services Task Force (USPSTF) stressing that people ages 60 or older should not take a daily baby aspirin for heart health ...
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Trends in aspirin use among U.S. adults. As noted by the current study, in 2019, there was a change in guidelines for aspirin use based on randomized trial data showing outcomes and risks of long ...
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