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The condition known today as diabetes (usually referring to diabetes mellitus) is thought to have been described in the Ebers Papyrus (c. 1550 BC). Ayurvedic physicians (5th/6th century BC) first noted the sweet taste of diabetic urine, and called the condition madhumeha ("honey urine").
Diabetes, also known as diabetes mellitus, is a group of common endocrine diseases characterized by sustained high blood sugar levels. [10] [11] Diabetes is due to either the pancreas not producing enough of the hormone insulin, or the cells of the body becoming unresponsive to insulin's effects. [12]
Diabetes was the eighth leading cause of death in the United States in 2020. People with diabetes are twice as likely to develop heart disease or stroke as people without diabetes. There are three types of diabetes: Type 1, Type 2, and gestational (diabetes while pregnant). Type 2 diabetes accounts for 90%-95% of all cases. [1]
When he died in 1993 at the age of 76, he became the world's first person to live 70 years with diabetes and probably the longest documented case of sustained insulin treatment in medical history. He was also the last survivor of the first twelve diabetes patients treated with insulin.
Their work led other doctors and scientists to pursue further research on the relation of the pancreas to diabetes, and ultimately resulted in the discovery of insulin as a treatment for the disease. Joseph von Mering, Oskar Minkowski: Diabetes mellitus nach Pankreasextirpation. Centralblatt für klinische Medicin, Leipzig, 1889, 10 (23): 393 ...
Elizabeth Evans Hughes Gossett (August 19, 1907 – April 21, 1981), the daughter of statesman Charles Evans Hughes, was the first American, and one of the first people in the world, treated with insulin for type 1 diabetes. She received over 42,000 insulin shots over her lifetime.
Type 1 diabetes (T1D), formerly known as juvenile diabetes, is an autoimmune disease that occurs when pancreatic cells (beta cells) are destroyed by the body's immune system. [5] In healthy persons, beta cells produce insulin. Insulin is a hormone required by the body to store and convert blood sugar into energy. [6]
Obesity increases the risk of many physical and mental conditions. These comorbidities are most commonly shown in metabolic syndrome, [2] a combination of medical disorders which includes: diabetes mellitus type 2, high blood pressure, high blood cholesterol, and high triglyceride levels. [49]