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5β-Dihydrotestosterone (5β-DHT), also known as 5β-androstan-17β-ol-3-one or as etiocholan-17β-ol-3-one, is an etiocholane (5β-androstane) steroid as well as an inactive metabolite of testosterone formed by 5β-reductase in the liver and bone marrow [1] [2] and an intermediate in the formation of 3α,5β-androstanediol and 3β,5β-androstanediol (by 3α-and 3β-hydroxysteroid ...
Androstanolone is available as a 2.5% hydroalcoholic gel given transdermally in doses of 5 or 10 g/day (brand name Andractim). [20] The medication was previously available as a 10 mg oral tablet with 300 mg L -lysine (brand name Lysinex) and as a 25 mg sublingual tablet (brand names Anabolex, Anaprotin, Anabolene, Anaboleen, Proteina).
Basic Instinct 2 (also known as Basic Instinct 2: Risk Addiction) is a 2006 erotic thriller film directed by Michael Caton-Jones, produced by Mario Kassar, Joel B. Michaels, and Andrew G. Vajna, and written by Leora Barish and Henry Bean.
DHT is a potent agonist of the AR, and is in fact the most potent known endogenous ligand of the receptor. It has an affinity (K d) of 0.25 to 0.5 nM for the human AR, which is about 2- to 3-fold higher than that of testosterone (K d = 0.4 to 1.0 nM) [47] and 15–30 times higher than that of adrenal androgens. [48]
Watch Paul Verhoeven's full Director's Reel below or needle-drop to 1:51 for the Basic Instinct discussion In recent years, though, Stone has pushed back against Verhoeven's version of events.
This is a list of 5α-reductase inhibitors (5α-RIs), drugs which inhibit one or more isoforms of the enzyme 5α-reductase.This enzyme is responsible for the conversion of the androgen hormone testosterone into the more potent dihydrotestosterone (DHT) and is essential for the production of neurosteroids like allopregnanolone, tetrahydrodeoxycorticosterone (THDOC), and 3α-androstanediol from ...