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  2. My Years of Leg Pain Turned Out to Be ALS: Why the ... - AOL

    www.aol.com/lifestyle/years-leg-pain-turned-als...

    Brooke Eby was diagnosed with ALS, or Lou Gehrig's disease, at 33 years old. It took four years for doctors to identify her condition; at the time, her primary symptom was a tightness in her calf ...

  3. ALS - Wikipedia

    en.wikipedia.org/wiki/ALS

    Amyotrophic lateral sclerosis (ALS), also known as motor neurone disease (MND) or (in the United States) Lou Gehrig's disease (LGD), is a rare, terminal neurodegenerative disorder that results in the progressive loss of both upper and lower motor neurons that normally control voluntary muscle contraction. [3]

  4. Primary lateral sclerosis - Wikipedia

    en.wikipedia.org/wiki/Primary_lateral_sclerosis

    Symptoms may include difficulty with balance, weakness and stiffness in the legs, and clumsiness. Other common symptoms are spasticity (involuntary muscle contraction due to the stretching of muscle, which depends on the velocity of the stretch) in the hands, feet, or legs, foot dragging , and speech and swallowing problems due to involvement ...

  5. Motor neuron diseases - Wikipedia

    en.wikipedia.org/wiki/Motor_neuron_diseases

    Symptoms of motor neuron diseases can be first seen at birth or can come on slowly later in life. Most of these diseases worsen over time; while some, such as ALS, shorten one's life expectancy, others do not. [2] Currently, there are no approved treatments for the majority of motor neuron disorders, and care is mostly symptomatic. [2]

  6. Christina Applegate says MS symptoms began 6 or 7 years ... - AOL

    www.aol.com/news/christina-applegate-says-ms...

    Most people's symptoms start between the ages of 20 and 40, and the disease is three times more common in women than in men, according to the National Institutes of Health and the nonprofit ...

  7. ALS Functional Rating Scale - Revised - Wikipedia

    en.wikipedia.org/wiki/ALS_Functional_Rating...

    Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease that typically affects adults around 54–67 [1] years of age, although anyone can be diagnosed with the disease. People diagnosed with ALS live on average 2–4 years after diagnosis due to the quick progression of the disease.

  8. 5 symptoms women over 40 should always take seriously - AOL

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    Women’s bodies go through many changes in menopause and the years leading up to it, known as perimenopause. This natural step in the aging process marks the end of the reproductive years. In ...

  9. Amyotrophic lateral sclerosis research - Wikipedia

    en.wikipedia.org/wiki/Amyotrophic_lateral...

    Using different BAC C9orf72 transgenic mouse model, they were able to study the symptoms of ALS, such as gait abnormalities, anxiety-like behavior, reduced grip strength, and even death rates. [8] Also, the denervation of motor neurons and dysfunction of neurons can be visualized using fluorescent markers to study the neurodegenerative disorder ...