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The Network of Cancer Genes (NCG) is a freely accessible web resource of genes that, when altered in their sequence, drive clonal expansion of normal tissues (healthy drivers) or cancer (cancer drivers). The project was launched in 2010 and has reached its 7th release in 2022.
G (1–4): the grade of the cancer cells (i.e. they are "low grade" if they appear similar to normal cells, and "high grade" if they appear poorly differentiated) S (0–3): elevation of serum tumor markers; R (0–2): the completeness of the operation (resection-boundaries free of cancer cells or not) Pn (0–1): invasion into adjunct nerves
An electronic forum, NGC-L for exchanging information on clinical practice guidelines, their development, implementation and use An Annotated Bibliography database where users can search for citations for publications and resources about guidelines, including guideline development and methodology, structure, evaluation, and implementation.
Gynecologic cancer is a type of cancer that affects the female reproductive system, including ovarian cancer, uterine cancer, vaginal cancer, cervical cancer, and vulvar cancer. Gynecological cancers comprise 10-15% of women's cancers, mainly affecting women past reproductive age but posing threats to fertility for younger patients. [ 1 ]
3D medical illustration depicting the TNM stages in breast cancer. Cancer staging can be divided into a clinical stage and a pathologic stage. In the TNM (Tumor, Node, Metastasis) system, clinical stage and pathologic stage are denoted by a small "c" or "p" before the stage (e.g., cT3N1M0 or pT2N0).
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Cervical cancer staging is described by the International Federation of Gynecology and Obstetrics . [12] [15] In 2018, FIGO released the most recent guidelines for cervical cancer staging. [16] These guidelines recommend the use of various physical examinations, types of imaging, and biopsies to determine the stage of cervical cancer. [16]
[1] [2] Just over 80% of women survive more than 5 years following diagnosis. [8] In 2015 about 3.8 million women were affected globally and it resulted in 90,000 deaths. [4] [5] Endometrial cancer is relatively common while uterine sarcomas are rare. [3] In the United States, uterine cancers represent 3.5% of new cancer cases. [8]