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  2. Tissue-type plasminogen activator - Wikipedia

    en.wikipedia.org/wiki/Tissue-type_plasminogen...

    Tissue-type plasminogen activator, short name tPA, is a protein that facilitates the breakdown of blood clots. It acts as an enzyme to convert plasminogen into its active form plasmin, the major enzyme responsible for clot breakdown. It is a serine protease (EC 3.4.21.68) found on endothelial cells lining the blood vessels.

  3. Plasminogen activator - Wikipedia

    en.wikipedia.org/wiki/Plasminogen_activator

    Plasminogen activator inhibitor-1 is a serine protease, synthesized by endothelial cells, that specifically inhibits tissue plasminogen activator (tPA) and urokinase (uPA). Tissue plasminogen activator and urokinase are the activators of plasminogen and result in the breakdown of blood clots (fibrinolysis). [4]

  4. Alteplase - Wikipedia

    en.wikipedia.org/wiki/Alteplase

    Alteplase, sold under the brand name Activase among others, is a biosynthetic form of human tissue-type plasminogen activator (t-PA). It is a thrombolytic medication used to treat acute ischemic stroke, acute ST-elevation myocardial infarction (a type of heart attack), pulmonary embolism associated with low blood pressure, and blocked central venous catheter. [5]

  5. Roper–Logan–Tierney model of nursing - Wikipedia

    en.wikipedia.org/wiki/Roper–Logan–Tierney...

    Nancy Roper, when interviewed by members of the Royal College of Nursing's (RCN) Association of Nursing Students at RCN Congress in 2002 in Harrogate [5] stated that the greatest disappointment she held for the use of the model in the UK was the lack of application of the five factors listed below, citing that these are the factors which make ...

  6. Streptokinase - Wikipedia

    en.wikipedia.org/wiki/Streptokinase

    Streptokinase is a thrombolytic medication activating plasminogen by nonenzymatic mechanism. [1] As a medication it is used to break down clots in some cases of myocardial infarction (heart attack), pulmonary embolism, and arterial thromboembolism. [2]

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  8. 12-O-Tetradecanoylphorbol-13-acetate - Wikipedia

    en.wikipedia.org/wiki/12-O-Tetradecanoylphorbol...

    12-O-Tetradecanoylphorbol-13-acetate (TPA), also commonly known as tetradecanoylphorbol acetate, tetradecanoyl phorbol acetate, and phorbol 12-myristate 13-acetate (PMA) is a diester of phorbol. It is a potent tumor promoter often employed in biomedical research to activate the signal transduction enzyme protein kinase C (PKC).

  9. Nursing process - Wikipedia

    en.wikipedia.org/wiki/Nursing_process

    The nursing process is a modified scientific method which is a fundamental part of nursing practices in many countries around the world. [1] [2] [3] Nursing practise was first described as a four-stage nursing process by Ida Jean Orlando in 1958. [4] It should not be confused with nursing theories or health informatics. The diagnosis phase was ...