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In 1847, Scottish obstetrician James Young Simpson (1811–1870) of Edinburgh was the first to use chloroform as a general anesthetic on a human (Robert Mortimer Glover had written on this possibility in 1842 but only used it on dogs). The use of chloroform anesthesia expanded rapidly thereafter in Europe.
William Thomas Green Morton (August 9, 1819 – July 15, 1868) was an American dentist and physician who first publicly demonstrated the use of inhaled ether as a surgical anesthetic in 1846. The promotion of his questionable claim to have been the discoverer of anesthesia became an obsession for the rest of his life. [1]
A balanced anesthesia protocol can be used whereby different drugs with different effects are used so that a high dose of just one drug can be avoided. For example, combining a sedative and an opioid will permit less inhalant anesthesia to be used, improving cardiovascular stability.
The first use of ether in dental surgery, by Ernest Board. Panel from Ether Monument in Boston commemorating Morton's demonstration of ether's anesthetic use. William T. G. Morton participated in a public demonstration of ether anesthesia on October 16, 1846, at the Ether Dome in Boston, Massachusetts.
The MGH Department of Anesthesia, Critical Care and Pain Medicine traces its roots back to the October 16, 1846 public demonstration of medical ether. Edward Gilbert Abbott (1825–1855) was the patient upon whom William T. G. Morton first publicly demonstrated the use of ether as a surgical anesthetic .
After observing the same physiological effects with diethyl ether ("ether") that Humphry Davy had described for nitrous oxide in 1800, Long used ether for the first time on March 30, 1842, to remove a tumor from the neck of a patient, James M. Venable. [7] He administered sulfuric ether on a towel and simply had the patient inhale. [8]
The Meyer-Overton correlation for anaesthetics. A nonspecific mechanism of general anaesthetic action was first proposed by Emil Harless and Ernst von Bibra in 1847. [9] They suggested that general anaesthetics may act by dissolving in the fatty fraction of brain cells and removing fatty constituents from them, thus changing activity of brain cells and inducing anaesthesia.
The Great Moment is a 1944 biographical film written and directed by Preston Sturges.Based on the book Triumph Over Pain (1940) by René Fülöp-Miller, it tells the story of Dr. William Thomas Green Morton, a 19th-century Boston dentist who discovered the use of ether for general anesthesia.