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Application of liquid nitrogen may cause burning or stinging at the treated site, which may persist for a few minutes after the treatment. With liquid nitrogen, a blister may form at the treatment site, but it will slough off in two to four weeks. Cryosurgery and curette scraping can be painful procedures and can result in residual scarring. [39]
Cryomassage is a type of massage involving the application of superficial cold to body tissue, [1] typically using ice or liquid nitrogen. [2] As a cryotherapy technique, cryomassage has been used to treat physical injury, [3] skin disorders [1] such as rosacea and facial erythrosis (redness), [2] and facial nerve neuropathy.
Severe cutaneous adverse reactions (SCARs) are a group of potentially lethal adverse drug reactions that involve the skin and mucous membranes of various body openings such as the eyes, ears, and inside the nose, mouth, and lips. In more severe cases, SCARs also involves serious damage to internal organs. SCARs includes five syndromes:
Medical cryotherapy gun with liquid nitrogen. In medical applications, spray cans containing dimethyl ether [4] or tetrafluoroethane may also be used to freeze and destroy tissue, for removal of warts and skin tags, or other uses in cryosurgery. Liquified petroleum gas including propane and butane is sometimes used.
By the 1940s, liquid nitrogen became more readily available, and the most common method of application was by means of a cotton applicator. In 1961, Cooper and Lee introduced a closed-system apparatus to spray liquid nitrogen. In the late 1960s, metal probes became available. By 1990, 87% of dermatologists used cryotherapy in their practice."
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