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Autocrine signaling involves a cell secreting a hormone or chemical messenger (called the autocrine agent) that binds to autocrine receptors on that same cell, leading to changes in the cell itself. [13] This can be contrasted with paracrine signaling, intracrine signaling, or classical endocrine signaling.
An antagonist is a chemical that acts within the body to reduce the physiological activity of another chemical substance (such as an opiate); especially one that opposes the action on the nervous system of a drug or a substance occurring naturally in the body by combining with and blocking its nervous receptor.
Homeometric autoregulation, in the context of the circulatory system, is the heart's ability to increase contractility and restore stroke volume when afterload increases. [6] Homeometric autoregulation occurs independently of cardiomyocyte fiber length, via the Bowditch and/or Anrep effects.
A chemical message is any compound that serves to transmit a message, and may refer to: Hormone, long range chemical messenger; Neurotransmitter, communicates to adjacent cells; Neuropeptide, a protein sequence which acts as a hormone or neurotransmitter. The blood or other body fluids transport neuropeptides to non adjacent target cells, where ...
Cardiac physiology or heart function is the study of healthy, unimpaired function of the heart: involving blood flow; myocardium structure; the electrical conduction system of the heart; the cardiac cycle and cardiac output and how these interact and depend on one another.
Autocrine signaling is a form of cell signaling in which a cell secretes a hormone or chemical messenger (called the autocrine agent) that binds to autocrine receptors on that same cell, leading to changes in the cell. [1] This can be contrasted with paracrine signaling, intracrine signaling, or classical endocrine signaling.
Like the average neuron, these cells conduct electrical impulses along the axon but unlike these neurons, neurosecretion produces neurohormones that are released into the body’s circulation. Combining the properties of the nervous and endocrine, these cells have the capacity to affect nerves through chemical messengers. [4]
The cardiovascular centre affects changes to the heart rate by sending a nerve impulse to the cardiac pacemaker via two sets of nerves: sympathetic fibres, part of the autonomic nervous system, to make heart rate faster. the vagus nerve, part of the parasympathetic branch of the autonomic nervous system, to lower heart rate.