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Important signs associated with genital ulcers that may assist in the diagnosis of the cause of the genital ulcer may include the presence of tender or non-tender enlarged lymph nodes in the groin area, a painful or non-painful genital ulcer, or the presence of vesicular lesions, which are small, painful, elevated blisters. [citation needed]
Genital herpes is a herpes infection of the genitals caused by the herpes simplex virus (HSV). [1] Most people either have no or mild symptoms and thus do not know they are infected. [ 1 ] When symptoms do occur, they typically include small blisters that break open to form painful ulcers . [ 1 ]
The infection spreads to the lymph nodes through lymphatic drainage pathways. The most frequent presenting clinical manifestation of LGV among males whose primary exposure was genital is unilateral (in two-thirds of cases) lymphadenitis and lymphangitis , often with tender inguinal and/or femoral lymphadenopathy because of the drainage pathway ...
Inguinal lymphadenopathy causes swollen lymph nodes in the groin area. It can be a symptom of infective or neoplastic processes. It can be a symptom of infective or neoplastic processes. Infective aetiologies include Tuberculosis, HIV , non-specific or reactive lymphadenopathy to recent lower limb infection or groin infections.
Inguinal spread can lead to the formation of pseudobubo without the involvement of the inguinal lymph nodes. The lesions frequently occur at the region of contact typically found on the shaft of the penis, the labia, or the perineum, and in the oral region due to oral intercourse. Rarely, the vaginal wall or cervix is the site of the lesion.
Painful swollen lymph nodes occur in 30–60% of patients. Dysuria (pain with urination) and dyspareunia (pain with intercourse) in females; About half of infected men have only a single ulcer. Women frequently have four or more ulcers, with fewer symptoms. The ulcers are typically confined to the genital region most of the time. [3]