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Intravenous use is contraindicated in patients with sinus bradycardia, sinoatrial block, second- or third-degree atrioventricular block, Stokes-Adams syndrome, or hypersensitivity to phenytoin, other hydantoins or any ingredient in the respective formulation.
Purple glove syndrome is caused by the intravenous anticonvulsant phenytoin. [3] This medication has many already established neurological side effects. However, glove syndrome is a rare, with prevalence ranging from 1.7% to 5.9%, but has very serious adverse effect that may lead to limb amputations.
Phenytoin/pentobarbital (trade name Beuthanasia-D Special) is an animal drug product used for euthanasia, which contains a mixture of phenytoin and pentobarbital. [1] It is administered as an intravenous injection to give animals a quick and humane death.
Fosphenytoin, also known as fosphenytoin sodium, and sold under the brand name Cerebyx among others, is a water-soluble phenytoin prodrug that is administered intravenously to deliver phenytoin, potentially more safely than intravenous phenytoin. It is used in the acute treatment of convulsive status epilepticus. Fosphenytoin was developed in 1996.
A euthanasia solution is a drug-containing aqueous solution for intentionally ending life to either relieve pain and suffering or execute convicts. [1] The drugs used in euthanasia solution do not only need to be safe to personnel, but they also need to have a rapid onset of action and minimize the possible pain felt by humans and animals. [2]
Bacterial meningitis, for instance, "requires immediate intravenous antibiotics and sometimes corticosteroids to reduce inflammation, while viral meningitis usually resolves on its own with rest ...
Throwing out the CFPB isn't a "Saturday Night Live" skit in the making, like, perhaps, President Donald Trump's executive order Feb. 10 to end the "procurement and forced use of paper straws.
Phenytoin, a CYP2C9 inducer, would increase its activity and the rate of warfarin breakdown, thereby reducing its efficacy. [23] Patients should avoid the co-administration of warfarin and phenytoin. In cases where both drugs must be used together, warfarin dosing may be titrated up to cope with the reduced efficacy. [24]