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Barbituric acid, the parent structure of all barbiturates. Barbiturates [a] are a class of depressant drugs that are chemically derived from barbituric acid. [2] They are effective when used medically as anxiolytics, hypnotics, and anticonvulsants, but have physical and psychological addiction potential as well as overdose potential among other possible adverse effects.
Human. Secobarbital is used in assisted dying, either euthanasia or palliative sedation. [8] [9] [10]In the Netherlands, individuals have two options for assisted dying: they can orally consume 100 mL of concentrated syrup containing either 15 grams of pentobarbital or 15 grams of secobarbital, or they can choose to have 2 grams of thiopental or 1 gram of propofol administered intravenously by ...
Butabarbital (brand name Butisol) is a prescription barbiturate sleep aid and anxiety medication.Butabarbital has a particularly fast onset of effects and short duration of action compared to other barbiturates, which makes it useful for certain applications such as treating severe insomnia, relieving general anxiety and relieving anxiety before surgical procedures; however it is also ...
The combination of a short-acting barbiturate, secobarbital, with an intermediate-acting barbiturate, amobarbital, aimed to provide "a rapid yet prolonged hypnotic action". [ 3 ] Eli Lilly has discontinued the manufacture of Tuinal in the United States due to the diminishing use of barbiturates (largely replaced by the benzodiazepine family of ...
Methohexital or methohexitone (marketed under the brand names Brevital and Brietal) is a drug which is a barbiturate derivative. It is classified as short-acting, and has a rapid onset of action. [2] It is similar in its effects to sodium thiopental, a drug with which it competed in the market for anesthetics.
Methylphenobarbital (), also known as mephobarbital (USAN, JAN) and mephobarbitone (), marketed under brand names such as Mebaral, Mephyltaletten, Phemiton, and Prominal, is a drug which is a barbiturate derivative and is used primarily as an anticonvulsant, [2] but also as a sedative and anxiolytic.
Phenobarbital, also known as phenobarbitone or phenobarb, sold under the brand name Luminal among others, is a medication of the barbiturate type. [6] It is recommended by the World Health Organization (WHO) for the treatment of certain types of epilepsy in developing countries. [8]
Pregabalin then appeared on the US market under the brand name Lyrica in the fall of 2005. [125] In 2017, the FDA approved pregabalin extended-release Lyrica CR for the management of neuropathic pain associated with diabetic peripheral neuropathy, and postherpetic neuralgia. [ 126 ]