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Gemfibrozil, sold under the brand name Lopid among others, is a medication used to treat abnormal blood lipid levels. [3] It is generally less preferred than statins . [ 3 ] [ 4 ] Use is recommended together with dietary changes and exercise. [ 3 ]
Gemfibrozil, an oral drug used to lower lipid levels; Nardosinone, a sesquiterpene; Octyl salicylate, an ingredient in sunscreens; Sterpuric acid, a sesquiterpene;
the cholesterol drug gemfibrozil This page was last edited on 29 December 2019, at 06:49 (UTC). Text is available under the Creative Commons ...
The following other wikis use this file: Usage on ar.wikipedia.org فايبرات; جمفبروزيل; Usage on azb.wikipedia.org جم فیبروزیل
Among atypical adverse effects, myositis can occur in patients under gemfibrozil therapy, especially in those with renal insufficiency or under co-treatment with statins. In contrast, the risk of myopathy is much lower if fenofibrate is used in replacement of gemfibrozil owing to its different pharmacokinetic pathway.
Fibrates are used in accessory therapy in many forms of hypercholesterolemia, but the combination of some fibrates (e.g., gemfibrozil) with statins is contraindicated due to an increased risk of rhabdomyolysis. [2]
Fenofibrate (sold under the brand name Tricor among others), is an oral medication of the fibrate class used to treat abnormal blood lipid levels. [3] It is less commonly used compared to statins because it treats a different type of cholesterol abnormality to statins.
Risks were higher in patients using fibrates, mainly gemfibrozil (Lopid), and in patients using the highest (0.8 mg/day) dose of cerivastatin. Bayer A.G. added a contraindication for the concomitant use of cerivastatin and gemfibrozil to the package 18 months after the drug interaction was found. [3]