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  2. Bottom-up and top-down design - Wikipedia

    en.wikipedia.org/wiki/Bottom–up_and_topdown...

    Information flow top-down and bottom-up in leadership. In the fields of management and organization, the terms "top-down" and "bottom-up" are used to describe how decisions are made and/or how change is implemented. [17] A "top-down" approach is where an executive decision maker or other top person makes the decisions of how something should be ...

  3. Top-down proteomics - Wikipedia

    en.wikipedia.org/wiki/Top-down_proteomics

    Top-down vs bottom-up proteomics. Top-down proteomics is a method of protein identification that either uses an ion trapping mass spectrometer to store an isolated protein ion for mass measurement and tandem mass spectrometry (MS/MS) analysis [1] [2] or other protein purification methods such as two-dimensional gel electrophoresis in conjunction with MS/MS. [3] Top-down proteomics is capable ...

  4. Bottom-up proteomics - Wikipedia

    en.wikipedia.org/wiki/Bottom-up_proteomics

    There is limited protein sequence coverage by identified peptides, loss of labile PTMs, and ambiguity of the origin for redundant peptide sequences. [7] Recently the combination of bottom-up and top-down proteomics, so called middle-down proteomics, is receiving a lot of attention as this approach not only can be applied to the analysis of large protein fragments but also avoids redundant ...

  5. Hierarchical clustering - Wikipedia

    en.wikipedia.org/wiki/Hierarchical_clustering

    Agglomerative: This is a "bottom-up" approach: Each observation starts in its own cluster, and pairs of clusters are merged as one moves up the hierarchy. Divisive: This is a "top-down" approach: All observations start in one cluster, and splits are performed recursively as one moves down the hierarchy.

  6. Pattern recognition (psychology) - Wikipedia

    en.wikipedia.org/wiki/Pattern_recognition...

    There are six main theories of pattern recognition: template matching, prototype-matching, feature analysis, recognition-by-components theory, bottom-up and top-down processing, and Fourier analysis. The application of these theories in everyday life is not mutually exclusive.

  7. Bottom-up parsing - Wikipedia

    en.wikipedia.org/wiki/Bottom-up_parsing

    Top-down parsing eagerly decides what a construct is much earlier, when it has only scanned the leftmost symbol of that construct and has not yet parsed any of its parts. Left corner parsing is a hybrid method that works bottom-up along the left edges of each subtree, and top-down on the rest of the parse tree.

  8. Top-down - Wikipedia

    en.wikipedia.org/wiki/Top-down

    Top-down reading, is a part of reading science that explains the reader's psycholinguistic strategies in using grammatical and lexical knowledge for comprehension rather than linearly decoding texts. Top-down proteomics, a method for protein analysis; Top-down effects, effects of population density on a resource in a soil food web

  9. Bottom-up - Wikipedia

    en.wikipedia.org/wiki/Bottom-up

    Bottom-up parsing, a computer science strategy; Bottom-up processing, in Pattern recognition (psychology) Bottom-up theories of galaxy formation and evolution; Bottom-up tree automaton, in data structures; Bottom-up integration testing, in software testing; Top-down and bottom-up design, strategies of information processing and knowledge ordering