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The oxygen enhancement ratio (OER) or oxygen enhancement effect in radiobiology refers to the enhancement of therapeutic or detrimental effect of ionizing radiation due to the presence of oxygen. This so-called oxygen effect [ 1 ] is most notable when cells are exposed to an ionizing radiation dose .
In biochemistry, the oxygen effect refers to a tendency for increased radiosensitivity of free living cells and organisms in the presence of oxygen than in anoxic or hypoxic conditions, where the oxygen tension is less than 1% of atmospheric pressure (i.e., <1% of 101.3 kPa, 760 mmHg or 760 torr).
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The relative biological effectiveness for radiation of type R on a tissue is defined as the ratio R B E = D X D R {\displaystyle RBE={\frac {D_{X}}{D_{R}}}} where D X is a reference absorbed dose of radiation of a standard type X , and D R is the absorbed dose of radiation of type R that causes the same amount of biological damage.
Oxygen enhancement ratio, effect magnitude of ionizing radiation due to the presence of oxygen; Oxygen Evolution Reaction, the formation of oxygen by electrochemical reduction of water; Owner’s Equivalent Rent, an economic metric for housing prices often used in the calculation of market baskets
Tumor stroma and extracellular matrix in hypoxia. Tumor hypoxia is the situation where tumor cells have been deprived of oxygen.As a tumor grows, it rapidly outgrows its blood supply, leaving portions of the tumor with regions where the oxygen concentration is significantly lower than in healthy tissues.
The ratio of partial pressure arterial oxygen and fraction of inspired oxygen, known as the Horowitz index or Carrico index, is a comparison between the oxygen level in the blood and the oxygen concentration that is breathed. This helps to determine the degree of any problems with how the lungs transfer oxygen to the blood. [5]
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