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Rarely, a bone affected by Paget's disease can transform into a malignant bone cancer. As the disease often affects people differently, treatments of Paget's disease can vary. Although there is no cure for Paget's disease, medications (bisphosphonates and calcitonin) can help control the disorder and lessen pain and other symptoms. Medications ...
Paget's disease of the breast (also known as mammary Paget's disease) is a rare skin change at the nipple nearly always associated with underlying breast cancer. [2] Paget's disease of the breast was first described by Sir James Paget in 1874. [3] The condition is an uncommon disease accounting for 1 to 4% of all breast cancers cases.
Paget's disease may refer to several conditions described by Sir James Paget, surgeon and pathologist: Paget's disease of bone (most common use of the term "Paget's disease") Paget's disease of the breast; Paget–Schroetter disease; Paget's abscess; Extramammary Paget's disease (EMPD)
[1] [2] It can manifest in localized or generalized osteosclerosis. Localized osteosclerosis can be caused by Legg–Calvé–Perthes disease, sickle-cell disease and osteoarthritis among others. Osteosclerosis can be classified in accordance with the causative factor into acquired and hereditary. [2] [1]
Extramammary Paget's disease (EMPD) is a rare and slow-growing cancer, which occurs within the epithelial tissues [1] and accounts for 6.5% of all Paget's disease. [2] This disease presents similarly to the more conventional form of mammary Paget's disease (MPD). [ 3 ]
Osteoporosis circumscripta cranii refers to a highly circumscribed (focal) lytic lesion of the skull bone as seen on X-ray in patients with Paget's disease of bones. [1] This focal lesion can be fairly large. This finding is highly specific for Paget's disease of bones.
Criminal Minds star Paget Brewster got candid about being “tempted” to get cosmetic surgery — but she still isn’t quite sure about it. “I’m pretty happy about how I look without ...
Leprosy, Paget's disease of bone Leonine facies is a facies that resembles that of a lion . It is seen in multiple conditions and has been classically described for lepromatous leprosy as well as Paget's disease of bone .