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An equianalgesic chart can be a useful tool, but the user must take care to correct for all relevant variables such as route of administration, cross tolerance, half-life and the bioavailability of a drug. [5] For example, the narcotic levorphanol is 4–8 times stronger than morphine, but also has a much longer half-life. Simply switching the ...
Anabolic steroid § Comparison of AAS; Template:Relative affinities of estrogens for steroid hormone receptors and blood proteins; Template:Affinities of estrogen receptor ligands for the ERα and ERβ; Template:Pharmacodynamics of progestogens
11β-Hydroxysteroid dehydrogenase (HSD-11β or 11β-HSD) enzymes catalyze the conversion of inert 11 keto-products to active cortisol, or vice versa, [1] thus regulating the access of glucocorticoids to the steroid receptors. The human genome encodes two distinct HSD-11β isozymes (HSD-11β Type 1 and HSD-11β Type 2) on distinct genes.
Addition of substituents at the C16 position can convert the steroid into an antiandrogen. Examples: oxendolone, metogest. Attachment of esters at the C3 and/or C17β hydroxyl groups confers increased lipophilicity and hence depot activity when administered in oil via intramuscular injection.
Most esters of these corticosteroids are not included in this list; for esters, see here instead. The most common structural modifications in synthetic corticosteroids include 1(2)-dehydrogenation, 6α-, 9α-, 16α-, and 16β-substitution (with a halogen or methyl group), 16α,17α-acetonidation, and 17α- and 21-esterification.
The steroid hormones are referred to by various abbreviations in the biological literature. The purpose of this list is to give commonly used abbreviations for steroid hormones, with supporting references to the literature.
List of steroidogenesis inhibitors – steroidogenesis inhibitors, or inhibitors of steroid biosynthesis and metabolism; As well as lists of steroid esters, including: List of androgen esters – androgen esters; List of estrogen esters – estrogen esters; List of progestogen esters – progestogen esters; List of corticosteroid esters ...
Corticosteroids are a class of steroid hormones that are produced in the adrenal cortex of vertebrates, as well as the synthetic analogues of these hormones.Two main classes of corticosteroids, glucocorticoids and mineralocorticoids, are involved in a wide range of physiological processes, including stress response, immune response, and regulation of inflammation, carbohydrate metabolism ...