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Cross-species transmission is the most significant cause of disease emergence in humans and other species. [citation needed] Wildlife zoonotic diseases of microbial origin are also the most common group of human emerging diseases, and CST between wildlife and livestock has appreciable economic impacts in agriculture by reducing livestock productivity and imposing export restrictions. [2]
The AIDS epidemic, caused by HIV (Human Immunodeficiency Virus), found its way to the United States between the 1970s and 1980s, [2] but was first noticed after doctors discovered clusters of Kaposi's sarcoma and pneumocystis pneumonia in homosexual men in Los Angeles, New York City, and San Francisco in 1981.
As of 2016, it is estimated that there are 1.5 million adults and children living with HIV/AIDS in North America, excluding Central America and the Caribbean. [ 1 ] 70,000 adults and children are newly infected every year, and the overall adult prevalence [ clarification needed ] is 0.5%.
HIV-1 is most similar to the SIV found in common chimpanzees (SIVcpz) in southeastern Cameroon, giving rise to the notion that HIV-1 emerged from chimpanzees in this area. [4] SIVcpz itself emerged in chimpanzees as the result of a recombination of two separate lineages of SIV known to infect red-capped mangabey , and Cercopithecus species.
Proponents of this dating link the HIV epidemic with the emergence of colonialism and growth of large colonial African cities, leading to social changes, including a higher degree of non-monogamous sexual activity, the spread of prostitution, and the concomitant high frequency of genital ulcer diseases (such as syphilis) in nascent colonial cities.
Initially identified as a central figure labeled "Patient Zero", Dugas faced allegations of being a primary source of HIV transmission to the United States. This narrative, popularized notably by Randy Shilts ' 1987 book And the Band Played On , has been refuted through subsequent scientific scrutiny and historical re-evaluation.
It did not last, but it does describe the shock of the announcement and the awareness that people had that maybe the stigma, maybe the stereotypes of who gets infected with HIV, are a wee bit too ...
HIV is a retrovirus that primarily infects components of the human immune system such as CD4 + T cells, macrophages and dendritic cells. It directly and indirectly destroys CD4 + T cells. [88] HIV is a member of the genus Lentivirus, [89] part of the family Retroviridae. [90] Lentiviruses share many morphological and biological characteristics.