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The Sysmex XE-2100 is a haematology automated analyser, used to quickly perform full blood counts and reticulocyte counts. It is made by the Sysmex Corporation. It can be run on its own, or connected to a blood film making and staining unit. Racks of blood go in on a tray on the right, and come out the left side.
Hematology analyzers (also spelled haematology analysers in British English) are used to count and identify blood cells at high speed with accuracy. [ 1 ] [ 2 ] [ 3 ] During the 1950s, laboratory technicians counted each individual blood cell underneath a microscope .
Sysmex Corporation (シスメックス株式会社, Shisumekkusu Kabushiki-gaisha) is a Japanese company headquartered in Kobe that is engaged in the health care business. Originally called TOA Medical Electronics (a branch of the TOA Corporation ), the Sysmex brand was established in 1978, and were mainly involved with haematology analysers.
Sysmex XT-4000i automated hematology analyzer The Coulter principle—the transient current drop is proportional to the particle volume To measure the hemoglobin concentration, a reagent chemical is added to the sample to destroy ( lyse ) the red cells in a channel separate from that used for red blood cell counts.
The white blood cell differential is a common blood test that is often ordered alongside a complete blood count.The test may be performed as part of a routine medical examination; to investigate certain symptoms, particularly those suggestive of infection or hematological disorders; [5] [6] or to monitor existing conditions, such as blood disorders and inflammatory diseases.
The AutoAnalyzer is an early example of an automated chemistry analyzer using a special flow technique named "continuous flow analysis (CFA)", invented in 1957 by Leonard Skeggs, PhD and first made by the Technicon Corporation. The first applications were for clinical (medical) analysis.
For example, for some patients with cold agglutinins, when their blood gets colder than 37 °C, the red cells will clump together. As a result, the analyzer may incorrectly report a low number of very dense red blood cells. This will result in an impossibly high number when the analyzer calculates the MCHC.
The U.S. Food and Drug Administration (FDA) defines analyte specific reagents (ASRs) in 21 CFR 864.4020 as “antibodies, both polyclonal and monoclonal, specific receptor proteins, ligands, nucleic acid sequences, and similar reagents which, through specific binding or chemical reaction with substances in a specimen, are intended to be used in a diagnostic application for identification and ...