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Sirolimus, also known as rapamycin and sold under the brand name Rapamune among others, is a macrolide compound that is used to coat coronary stents, prevent organ transplant rejection, treat a rare lung disease called lymphangioleiomyomatosis, and treat perivascular epithelioid cell tumour (PEComa).
Paradoxically, even though rapamycin is a federally approved immunosuppressant, its inhibition of mTORC1 results in better quantity and quality of functional memory T cells. mTORC1 inhibition with rapamycin improves the ability of naïve T cells to become precursor memory T cells during the expansion phase of T cell development . [78]
The mammalian target of rapamycin (mTOR), [5] also referred to as the mechanistic target of rapamycin, and sometimes called FK506-binding protein 12-rapamycin-associated protein 1 (FRAP1), is a kinase that in humans is encoded by the MTOR gene. [6] [7] [8] mTOR is a member of the phosphatidylinositol 3-kinase-related kinase family of protein ...
Food and agriculture nonprofits (FANOs) are an understudied player in food system sustainability and food waste management ([81]). FANOs play an essential role at every step of the food supply chain ([81]) including in creating or preventing food waste ). Food waste can be defined as edible food discarded by consumers.
The Bio-medical Waste (Management and Handling) Rules, 1998 and further amendments were passed for the regulation of bio-medical waste management. On 28 March 2016 Biomedical Waste Management Rules (BMW 2016) [15] were also notified by Central Govt. Each state's Pollution Control Board or Pollution control Committee will be responsible for ...
WMP Waste Management Plan; WMPEG Waste Minimisation Performance and Efficiency Grant; WMS Waste Management Strategy; WRAP Waste and Resources Action Programme; WRATE Waste and Resources Assessment Tool for the Environment; WRG Waste Recycling Group; WRWA Western Riverside Waste Authority; WS2007 Waste Strategy for England 2007 (superseded by ...
Waste treatment refers to the activities required to ensure that waste has the least practicable impact on the environment. In many countries various forms of waste treatment are required by law. In many countries various forms of waste treatment are required by law.
Waste comes in many different forms and may be categorized in a variety of ways. The types listed here are not necessarily exclusive and there may be considerable overlap so that one waste entity may fall into one to many types.