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Mitral valve prolapse (MVP) is a valvular heart disease characterized by the displacement of an abnormally thickened mitral valve leaflet into the left atrium during systole. [4] It is the primary form of myxomatous degeneration of the valve. There are various types of MVP, broadly classified as classic and nonclassic.
Myxomatous degeneration of the mitral valve is more common in women as well as with advancing age, which causes a stretching of the leaflets of the valve and the chordae tendineae. Such elongation prevents the valve leaflets from fully coming together when the valve closes, causing the valve leaflets to prolapse into the left atrium, thereby ...
With mitral valve prolapse the connective tissue of the leaflets and surrounding tissue are weakened, called myxomatous degeneration. Why this happens isn’t well understood, but it is sometimes associated with connective tissue disorders like Marfan syndrome and Ehlers-Danlos syndrome.
Myxoma is a rare, benign stromal tumor of mesenchymal origin often confused with other conjunctival stromal tumors. Conjunctival myxomas are thought to originate in Tenon's capsule and can masquerade as conjunctival lymphoma, lymphangioma, ocular surface squamous neoplasia (OSSN), or amelanotic melanoma.
Myxomata are the most common primary cardiac tumor in adults, and are most commonly found within the left atrium near the valve of the fossa ovalis. Myxoma may also develop in the other heart chambers. [1] The tumor is derived from multipotent mesenchymal cells. [1] Cardiac myxoma can affect adults between 30 and 60 years of age. [2]
This test can also show leaflet calcification and the pressure gradient over the mitral valve. [32] Severe mitral stenosis is defined as a mitral valve area <1.5 cm 2. [8] Progressive mitral stenosis has a normal valve area but will have increased flow velocity across the mitral valve. [8]
Mitral valve agenesis is very rare, defined as an absence or minimal presence of both mitral valve leaflets (complete agenesis) or one of the leaflets (partial agenesis). [16] Surgery can be performed to replace or repair a damaged valve. A less invasive method is that of mitral valvuloplasty which uses a balloon catheter to open up a stenotic ...
The valve leaflets are separated by two commissures, and each leaflet of the valve (anterior leaflet, the large one, and posterior leaflet, the small one) has three sections (p1, p2, p3). Histologically, each leaflet is composed of the solid fibrosa, the spongiosa at the atrial surface and another fibroelastic layer covering the leaflets. [ 2 ]