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  2. Signs and symptoms of HIV/AIDS - Wikipedia

    en.wikipedia.org/wiki/Signs_and_symptoms_of_HIV/AIDS

    The latency stage involves few or no symptoms and can last anywhere from two weeks to twenty years or more, depending on the individual. AIDS, the final stage of HIV infection, is defined by low CD4+ T cell counts (fewer than 200 per μL), various opportunistic infections, cancers, and other conditions.

  3. HIV/AIDS - Wikipedia

    en.wikipedia.org/wiki/HIV/AIDS

    Without treatment, this second stage of the natural history of HIV infection can last from about three years [34] to over 20 years [35] (on average, about eight years). [36] While typically there are few or no symptoms at first, near the end of this stage many people experience fever, weight loss, gastrointestinal problems and muscle pains. [1]

  4. WHO Disease Staging System for HIV Infection and Disease in ...

    en.wikipedia.org/wiki/WHO_Disease_Staging_System...

    Conditions where a presumptive diagnosis can be made on the basis of clinical signs or simple investigations [citation needed] Unexplained chronic diarrhoea for longer than one month; Unexplained persistent fever (intermittent or constant for longer than one month) Severe weight loss (>10% of presumed or measured body weight) Oral candidiasis

  5. HIV set point - Wikipedia

    en.wikipedia.org/wiki/HIV_set_point

    The asymptomatic or clinical latency phase is marked by slow replication of the HIV virus, followed by steady depletion of CD4 T cells with little to no symptoms. For individuals that are rapid progressors, this phase can be short lived, with an average of 2-3 years. Long-term progressors (LTNPS) can remain stable in this stage for over a ...

  6. HIV latency - Wikipedia

    en.wikipedia.org/wiki/HIV_latency

    This model proposes to explain why many latent proviruses are not reactivated along with T-cell reactivation: instead of a deterministic mechanism, cellular activation or relaxation would probabilistically affect HIV latency decisions, [12] which is consistent with other work showing that LTR regulatory sites have some influence on the ...

  7. Pathophysiology of HIV/AIDS - Wikipedia

    en.wikipedia.org/wiki/Pathophysiology_of_HIV/AIDS

    The reason for the preferential loss of mucosal CD4 + T cells is that a majority of mucosal CD4 + T cells express the CCR5 coreceptor, whereas a small fraction of CD4 + T cells in the bloodstream do so. [5] HIV seeks out and destroys CCR5 expressing CD4 + cells during acute infection. A vigorous immune response eventually controls the infection ...

  8. Ozempic reduces severity of liver disease in people with HIV ...

    www.aol.com/news/ozempic-reduces-severity-liver...

    (Reuters) -A weekly injection of semaglutide was safe and reduced the amount of fat in the liver by 31% in people with HIV and a type of liver disease, data from a mid-stage study funded by the ...

  9. HIV disease progression rates - Wikipedia

    en.wikipedia.org/wiki/HIV_disease_progression_rates

    Multiple studies of HIV-infected persons have shown that the presence of one copy of this mutation, named CCR5-Δ32 (CCR5 delta 32) delays progression to the condition of AIDS by about 2 years. [citation needed] The National Institute of Health (NIH) has funded research studies to learn more about this genetic mutation. In such research, NIH ...