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Sickle cell disease (SCD), also simply called sickle cell, is a group of hemoglobin-related blood disorders typically inherited. [2] The most common type is known as sickle cell anemia. [2] It results in an abnormality in the oxygen-carrying protein haemoglobin found in red blood cells. [2] This leads to a rigid, sickle -like shape under ...
Neel first found the inheritance of sickle cell anemia through its genetic basis. This was the first step to learning all of what we know genetically about sickle cell disease. He found that the sickle cell trait itself was heterozygous and the disease was expressed when the gene was recessive homozygous.
The Sickle Cell Disease Association of America, Inc. originated in Racine, Wisconsin. Representatives from 15 different community-based sickle cell organizations came together at Wingspread, a community center, as guest of the Johnson Foundation. There was a common belief that there was a need for national attention to sickle cell disease.
The FDA approved a new treatment for sickle cell disease. The therapy is first to use the ground-editing tool CRISPR. ... Using CRISPR, it edits the DNA found in a patient’s stem cells to remove ...
A Rapid Diagnostic Test for Sickle Cell Anemia (1950) Harvey Akio Itano (Japanese: ハーベイ・アキオ・イタノ[1], November 3, 1920 – May 8, 2010) was an American biochemist best known for his work on the molecular basis of sickle cell anemia and other diseases. In collaboration with Linus Pauling, Itano used electrophoresis to ...
A study published in 2013 found that patients seeking care from 2003 through 2008 at an ER for their sickle cell crises experienced 50% longer wait times than patients who arrived at ERs with ...
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Anthony Clifford Allison (21 August 1925 – 20 February 2014) was a South African geneticist and medical scientist who made pioneering studies on the genetic resistance to malaria. [2] Clark completed his primary schooling in Kenya, completed his higher education in South Africa, and obtained a BSc in medical science from the University of the ...