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  2. About Flavoring-related Lung Disease - CDC

    www.cdc.gov/niosh/flavoring-related-lung-disease

    Key points. Flavoring-related lung disease is caused by the flavoring chemical diacetyl (2,3-butanedione) and its substitute, 2,3-pentanedione (acetyl propionyl). Flavoring chemicals are used in food flavoring and production industries. Workers exposed to these flavoring chemicals are at risk of severe respiratory impairment.

  3. Fixed Obstructive Lung Disease in Workers at a Microwave Popcorn...

    www.cdc.gov/mmwr/preview/mmwrhtml/mm5116a2.htm

    Public health authorities, employers, and health-care providers are collaborating to prevent obstructive lung disease in popcorn factory workers. At factory A, soybean oil, salt, and flavorings are mixed into a large heated tank in a process that produces visible dust, aerosols, and vapors with a strong buttery odor.

  4. Update: Characteristics of a Nationwide Outbreak of E-cigarette...

    www.cdc.gov/mmwr/volumes/69/wr/mm6903e2.htm

    Taylor J, Wiens T, Peterson J, et al. Characteristics of e-cigarette, or vaping, products used by patients with associated lung injury and products seized by law enforcement—Minnesota, 2018 and 2019. MMWR Morb Mortal Wkly Rep 2019;68:1096–1100. Food and Drug Administration. Lung illnesses associated with use of vaping products.

  5. Preventing Lung Disease in Workers: Who Use or Make Flavorings [PDF – 453 KB] This Alert describes health effects that may occur because of workplace exposure to some flavorings or their ingredients, gives examples of workplace settings in which illness has occurred, and recommends steps that companies and workers should take to prevent ...

  6. Preventing Lung Disease in Workers Who Use or Make Flavorings

    www.cdc.gov/niosh/docs/2004-110/pdfs/2004-110.pdf?id=10.26616/NIOSHPUB2004110

    severe lung disease in workers at a micro-wave popcorn packaging plant. Eight for-mer workers at this plant developed illness characterized by fixed airways obstruction on lung function tests [Akpinar-Elci et al. 2002]. An evaluation of the current workforce at this plant showed an association be-tween exposure to vapors from flavorings

  7. Fixed Obstructive Lung Disease Among Workers in the Flavor ...

    www.cdc.gov/mmwr/preview/mmwrhtml/mm5616a2.htm

    Bronchiolitis obliterans, a rare and life-threatening form of fixed obstructive lung disease, is known to be caused by exposure to noxious gases in occupational settings and has been described in workers in the microwave-popcorn industry who were exposed to artificial butter-flavoring chemicals, including diacetyl (1,2). In August 2004, the ...

  8. Diacetyl and its substitute, 2,3-pentanedione, are widely used as flavoring compounds. The National Institute for Occupational Safety and Health (NIOSH) objective in establishing recommended exposure limits (RELs) for diacetyl and 2,3-pentanedione is to reduce the risk of respiratory impairment (decreased lung function) and the severe irreversible lung disease obliterative bronchiolitis ...

  9. In addition, because the specific compound or ingredient causing lung injury is not yet known, CDC continues to recommend that persons consider refraining from use of all e-cigarette, or vaping, products while the outbreak investigation continues (1).

  10. Update: Interim Guidance for Health Care Providers ...

    www.cdc.gov/mmwr/volumes/68/wr/mm6841e3.htm

    Characteristics of a multistate outbreak of lung injury associated with e-cigarette use, or vaping—United States, 2019. MMWR Morb Mortal Wkly Rep 2019;68:860–4. CrossRef PubMed; Ghinai I, Pray IW, Navon L, et al. E-cigarette product use, or vaping, among persons with associated lung injury—Illinois and Wisconsin, April–September 2019.

  11. CRITERIA FOR A RECOMMENDED STANDARD Occupational Exposure to...

    www.cdc.gov/niosh/docket/archive/pdfs/NIOSH-245/0245-081211-draftdocument.pdf

    concentration should have no more than a 1 in 1000 chance of suffering reduced lung function associated with diacetyl exposure and less chance for developing bronchiolitis obliterans. To further protect against effects of short-term exposures, NIOSH recommends a short-term exposure limit (STEL) for diacetyl of 25 ppb for a 15-minute time period.