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More recently, enzyme molecules have also shown positive chemotactic behavior in the gradient of their substrates. [78] The thermodynamically favorable binding of enzymes to their specific substrates is recognized as the origin of enzymatic chemotaxis. [79] Additionally, enzymes in cascades have also shown substrate-driven chemotactic ...
The main discussion of these abbreviations in the context of drug prescriptions and other medical prescriptions is at List of abbreviations used in medical prescriptions. Some of these abbreviations are best not used, as marked and explained here.
Radial arrangement of PP-technique (3 or more channels) provides the possibility to compare chemotactic activity of different cell populations or study preference between ligands. [ 1 ] Counting of cells: positive responder cells could be counted from the front of migrating cells, after staining or in native conditions in light microscope.
The CC chemokine (or β-chemokine) proteins have two adjacent cysteines (amino acids), near their amino terminus. There have been at least 27 distinct members of this subgroup reported for mammals, called CC chemokine ligands -1 to -28; CCL10 is the same as CCL9. Chemokines of this subfamily usually contain four cysteines (C4-CC chemokines ...
By chemotactic selection we can determine whether a still not characterized molecule acts via the long- or the short-term receptor pathway. Recent results proved that chemokines (e.g. IL-8 , RANTES ) are working on long-term chemotaxis receptors, while vasoactive peptides (e.g. endothelin ) act more on the short-term ones.
In cellular biology, haptotaxis (from Greek ἅπτω (hapto) 'touch, fasten' and τάξις (taxis) 'arrangement, order') is the directional motility or outgrowth of cells, e.g. in the case of axonal outgrowth, usually up a gradient of cellular adhesion sites or substrate-bound chemoattractants (the gradient of the chemoattractant being expressed or bound on a surface, in contrast to the ...
The mechanism of the chemorepulsion of immune cells was first acknowledged by medical researchers at the Massachusetts General Hospital in Boston in early 2002. [1] The phenomenon was originally referred to as "reverse chemotaxis ," and later, “fugetaxis” (derived from the Latin words fugere , to flee from; and taxis , movement). [ 1 ]
In asthma patients, there is an observed increase in the levels of eotaxin. The evidence of this comes from bronchial biopsies, where they have seen an increase of eotaxin levels in asthmatic individuals. The increased levels are associated with airway hyperresponsiveness. These levels have also been associated with airway obstruction. [3]