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  2. Vitamin K2 - Wikipedia

    en.wikipedia.org/wiki/Vitamin_K2

    Vitamin K2 may have a protective effect on bone mineral density and reduced risk of hip, vertebral and non-vertebral fractures. [11] These effects appear to be accentuated when combined with vitamin D and in the setting of osteoporosis. [1] Research suggests that vitamin K 2 (Menaquinone 7, MK-7]) may reduce the rate and severity of night time ...

  3. Vitamin D - Wikipedia

    en.wikipedia.org/wiki/Vitamin_D

    For example, CYP11A1, an enzyme chiefly known for its role in steroidogenesis, has been found to hydroxylate vitamin D3 at several positions, including C-20, C-22, and C-23, without cleaving the side chain. The resulting metabolites, such as 20-hydroxyvitamin D3 and 20,23-dihydroxyvitamin D3, act as inverse agonists for RORα and RORγ2.

  4. Vitamin K - Wikipedia

    en.wikipedia.org/wiki/Vitamin_K

    Vitamin K is a family of structurally similar, fat-soluble vitamers found in foods and marketed as dietary supplements. [1] The human body requires vitamin K for post-synthesis modification of certain proteins that are required for blood coagulation ("K" from Danish koagulation, for "coagulation") or for controlling binding of calcium in bones and other tissues. [2]

  5. Vitamin D toxicity - Wikipedia

    en.wikipedia.org/wiki/Vitamin_D_toxicity

    Vitamin D compounds, specifically cholecalciferol (D3) and ergocalciferol (D2) are used in rodenticides due to their ability to induce hypercalcemia, a condition characterized by elevated calcium levels in the blood. This overdose leads to organ failure and is pharmacologically similar to vitamin D's toxic effects in humans.

  6. Calcitriol - Wikipedia

    en.wikipedia.org/wiki/Calcitriol

    Calcitriol is a hormone and the active form of vitamin D, normally made in the kidney. [8] [9] [10] It is also known as 1,25-dihydroxycholecalciferol.It binds to and activates the vitamin D receptor in the nucleus of the cell, which then increases the expression of many genes. [11]

  7. Vitamin K reaction - Wikipedia

    en.wikipedia.org/wiki/Vitamin_K_reaction

    There has been rare reports of oral vitamin K adverse effects. Intravenous vitamin K admission had reports of low blood pressure, shortness of breath, flushing, and other serious allergic reactions. [ 6 ] [ 13 ] Vitamin K needs to be diluted to an aqueous solution for administration as a it is a fat-soluble vitamin.