Search results
Results From The WOW.Com Content Network
HMG-box containing proteins only bind non-B-type DNA conformations (kinked or unwound) with high affinity. [1]HMG-box domains are found in some high mobility group proteins, which are involved in the regulation of DNA-dependent processes such as transcription, replication, and DNA repair, all of which require changing the conformation of chromatin. [3]
The SRY gene on the Y Chromosome, responsible for male sexual differentiation, contains an HMG-Box domain. A member of the HMG family of proteins, HMGB1, has also been shown to have an extracellular activity as a chemokine, attracting neutrophils and mononuclear inflammatory cells to the infected liver. [3]
SOX genes (SRY-related HMG-box genes) encode a family of transcription factors that bind to the minor groove in DNA, and belong to a super-family of genes characterized by a homologous sequence called the HMG-box (for high mobility group). This HMG box is a DNA binding domain that is highly conserved throughout eukaryotic species. Homologues ...
6657 20674 Ensembl ENSG00000181449 ENSMUSG00000074637 UniProt P48431 P48432 RefSeq (mRNA) NM_003106 NM_011443 RefSeq (protein) NP_003097 NP_035573 Location (UCSC) Chr 3: 181.71 – 181.71 Mb Chr 3: 34.7 – 34.71 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse SRY (sex determining region Y)-box 2, also known as SOX2, is a transcription factor that is essential for maintaining self ...
HMGB1 has to interact with p53. [15] [16]HMGB1 is a nuclear protein that binds to DNA and acts as an architectural chromatin-binding factor. It can also be released from cells, an extracellular form in which it may bind to toll-like receptors (TLRs) or an inflammatory receptor called the receptor for advanced glycation end-products RAGE.
The ensuing madness was one of the wilder and weirder stories in NFL lore — part who done it, part high-paid legal drama, part science lesson, part Rorschach test, part character assassination ...
6662 20682 Ensembl ENSG00000125398 ENSMUSG00000000567 UniProt P48436 Q04887 RefSeq (mRNA) NM_000346 NM_011448 RefSeq (protein) NP_000337 NP_035578 Location (UCSC) Chr 17: 72.12 – 72.13 Mb Chr 11: 112.67 – 112.68 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Transcription factor SOX-9 is a protein that in humans is encoded by the SOX9 gene. Function SOX-9 recognizes the sequence ...
Hoka is one of the most popular brands of running and walking shoes out there today, and if you want a white sneaker that marries style and performance, we highly recommend the new Clifton 9.