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In pharmacology, the fibrates are a class of amphipathic carboxylic acids and esters. They are derivatives of fibric acid (phenoxyisobutyric acid). They are used for a range of metabolic disorders, mainly hypercholesterolemia (high cholesterol ), and are therefore hypolipidemic agents .
Fibrates are hypolipidemic agents primarily used for decreasing serum triglycerides, while increasing High density lipoprotein (HDL). Wikimedia Commons has media related to Fibrates . Subcategories
It belongs to the fibrates group of medications and works by decreasing the breakdown of lipids in fat cells. [3] Gemfibrozil was patented in 1968, and came into medical use in 1982. [6] It is available as a generic medication. [4] In 2022, it was the 231st most commonly prescribed medication in the United States, with more than 1 million ...
How many of these brain busters can you solve? The post 25 Printable Brain Teasers You Can Print for Free appeared first on Reader's Digest.
And if you’re looking for a caffeine jolt that you can get from some sodas, iced coffee is a good swap as long as you go easy on the sugars, syrups and creamers. This article was originally ...
You may improve this article, discuss the issue on the talk page, or create a new article, as appropriate. ( December 2010 ) ( Learn how and when to remove this message ) Fibre supplements (also spelled fiber supplements ) are considered to be a form of a subgroup of functional dietary fibre , and in the United States are defined by the ...
Bezafibrate (marketed as Bezalip and various other brand names) is a fibrate drug used as a lipid-lowering agent to treat hyperlipidaemia. It helps to lower LDL cholesterol and triglyceride in the blood, and increase HDL. It was patented in 1971 and approved for medical use in 1978. [1]
The cholesterol lowering effect of fibrates is due to their ability to activate a nuclear receptor called peroxisome proliferator activated receptor alpha. [20] [21] They include fenofibrate, gemfibrozil, and bezafibrate and work to decrease triglycerides, increase HDL-C, and also decrease LDL-C which is variable depending on which drug is used.