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Dermatomyositis is an autoimmune disorder featuring both humoral and T-cell autoimmune processes. [3] Dermatomyositis may develop as a paraneoplastic syndrome associated with several forms of malignancy. [4] It is known to be associated with several viruses, especially coxsackievirus, but no definitive causal link has been found. [3]
Gottron's sign is a pathognomonic cutaneous manifestation associated with dermatomyositis (DM), which is an inflammatory disorder affecting the skin and muscles. [1] The primary lesion of dermatomyositis appears as a violaceous, macular erythema with a symmetric distribution, which may progress and become poikilodermatous (atrophic with telangiectasia and pigmentary changes) and indurated (as ...
dermatomyositis: Pathologic Basis of Disease (8th Ed), Robbins & Cotran: Scaling, erythematous eruption or dusky red patches over the knuckles, elbows and knees Gowers' sign [3] William Richard Gowers: neurology: muscular dystrophy: Graham Steell murmur: Graham Steell: cardiology: mitral stenosis
Polymyositis and dermatomyositis [ edit ] In severe cases of PM and DM with systemic signs, an initial three to five days on intravenous corticosteroid ( methylprednisolone ) may be used; but normally treatment begins with a single daily (after breakfast) high dose of oral corticosteroid ( prednisone ).
The three main types of idiopathic myositis (known as inflammatory myopathies) that typically test positive for autoantibodies are dermatomyositis, polymyositis, and inclusion body myositis. [4] Other autoimmune diseases, such as systemic lupus erythematosus , can also cause myositis-like symptoms.
These signs include: Fever, chills, neck pain, fatigue, inability to look at bright light, or inability to eat or drink. “If you have those symptoms, it’s time to go to the emergency room.
When sIBM was originally described, the major feature noted was muscle inflammation. Two other disorders were also known to display muscle inflammation, and sIBM was classified along with them. They are dermatomyositis (DM) and polymyositis (PM) and all three illnesses were called idiopathic (of unknown origin) myositis or inflammatory ...
Dermatomyositis produces muscle weakness and skin changes. The skin rash is reddish and most commonly occurs on the face, especially around the eyes, and over the knuckles and elbows. Ragged nail folds with visible capillaries can be present. It can often be treated by drugs like corticosteroids or immunosuppressants. (M33.2)