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A 2019 systematic review published by the National Kidney Foundation investigated whether creatine supplementation had adverse effects on renal function. [72] They identified 15 studies from 1997 to 2013 that looked at standard creatine loading and maintenance protocols of 4–20 g/day of creatine versus placebo.
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Kidney toxicity [5] associated with kidney failure; associated with development of cancer, particularly of the urinary tract, known carcinogen [8] [9] Atractylate Atractylis gummifera: Liver damage, [3] nausea, vomiting, epigastric and abdominal pain, diarrhoea, anxiety, headache and convulsions, often followed by coma [10]
People on dialysis must follow dietary restrictions, making it difficult for them to get the necessary amounts of certain vitamins and minerals to stay healthy. [3] In addition, vitamins and minerals are lost during the process of dialysis. Therefore, dialysis patients are at risk for vitamin and mineral deficiencies.
Serum creatinine (a blood measurement) is an important indicator of kidney function, because it is an easily measured byproduct of muscle metabolism that is excreted unchanged by the kidneys. Creatinine itself is produced [ 5 ] via a biological system involving creatine , phosphocreatine (also known as creatine phosphate), and adenosine ...
Some herbs may amplify the effects of anticoagulants. [51] Certain herbs as well as common fruit interfere with cytochrome P450, an enzyme critical to much drug metabolism. [52] In a 2018 study, the FDA identified active pharmaceutical additives in over 700 analyzed dietary supplements sold as "herbal", "natural" or "traditional". [53]
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