Ads
related to: hydrochlorothiazide and gout increase
Search results
Results From The WOW.Com Content Network
All thiazide diuretics including hydrochlorothiazide can inhibit excretion of uric acid by the kidneys, thereby increasing serum concentrations of uric acid. This may increase the incidence of gout in doses of ≥ 25 mg per day and in more susceptible patients such as male gender of <60 years old. [23] [24] [25] Hyperglycemia, high blood sugar
Avoid foods that cause gout, including those with high-fructose corn syrup, like sodas, juice drinks, and sweets, which can increase uric acid production. Drink plenty of water to help flush uric ...
Diuretics have been associated with attacks of gout, but a low dose of hydrochlorothiazide does not seem to increase risk. [39] Other medications that increase the risk include niacin, aspirin (acetylsalicylic acid), ACE inhibitors, angiotensin receptor blockers, beta blockers, ritonavir, and pyrazinamide.
Thiazides combined with potassium citrate, increased water intake and decreased dietary oxalate and sodium can slow or even reverse the formation of calcium-containing kidney stones. [18] High-dose therapy with the thiazide-like diuretic indapamide can be used to treat idiopathic hypercalcinuria (high urine calcium with unknown cause).
Infrequent ADRs include: dyslipidemia, increased serum creatinine concentration, hypocalcemia, rash. Metabolic alkalosis may also be seen with loop diuretic use. [citation needed] Ototoxicity (damage to the inner ear) is a serious, but rare ADR associated with use of loop diuretics.
Uricosurics are often used in the treatment of gout, a disease in which uric acid crystals form deposits in the joints. By decreasing plasma uric acid levels, help dissolve these crystals, while limiting the formation of new ones. However, the increased uric acid levels in urine can contribute to kidney stones.
[2] [3] [6] Other adverse effects may include gout, low blood magnesium, high blood calcium, allergic reactions, and low blood pressure. [2] [3] [7] Some reviews have found chlortalidone and hydrochlorothiazide to have a similar risk of adverse effects, [8] [9] while other reviews have found chlortalidone to have a higher risk.
Unless high blood levels of uric acid are determined in a clinical laboratory, hyperuricemia may not cause noticeable symptoms in most people. [5] Development of gout – which is a painful, short-term disorder – is the most common consequence of hyperuricemia, which causes deposition of uric acid crystals usually in joints of the extremities, but may also induce formation of kidney stones ...